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Startseva O.I.

Rossiĭskiĭ nauchnyĭ tsentr khirurgii im. akad. B.V. Petrovskogo RAMN, Moskva

Sinelnikov M.E.

Sechenov First Moscow State Medical University, Moscow, Russia

Babayeva Yu.V.

Sechenov First Moscow State Medical University, Moscow, Russia

Trushenkova V.V.

Sechenov First Moscow State Medical University, Moscow, Russia

Decellularization of organs and tissues

Authors:

Startseva O.I., Sinelnikov M.E., Babayeva Yu.V., Trushenkova V.V.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2019;(8): 59‑62

DOI: 10.17116/hirurgia201908159

Read: 3940 times

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Table of contents

DECELLULARIZATION OF ORGANS AND TISSUES
DECELLULARIZATION OF ORGANS AND TISSUES

To cite this article:

Startseva OI, Sinelnikov ME, Babayeva YuV, Trushenkova VV. Decellularization of organs and tissues. Pirogov Russian Journal of Surgery. 2019;(8):59‑62. (In Russ.)
https://doi.org/10.17116/hirurgia201908159

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The use of allogenic materials in reconstructive surgery is of great scientific interest due to high availability of donor tissues. The positive aspects of allogenous tissue transplantation are complicated by the histological incompatibility of donor tissue and recipient organism. This incompatibility results hypersensitivity reaction towards the allogenous transplant followed by rejection of allogenic tissue and even death in some cases. Cellular biological incompatibility may be managed by decellularization of allogenous organs and tissues prior to transplantation. The improvement of decellularization techniques will facilitate application of allogenous tissues in complex reconstructive procedures and significantly increase the capabilities of reconstructive surgery.

Keywords:

decellularization
cellular disaggregation
allogenous transplantation
reconstructive surgery

Authors:

Startseva O.I.

Rossiĭskiĭ nauchnyĭ tsentr khirurgii im. akad. B.V. Petrovskogo RAMN, Moskva

Sinelnikov M.E.

Sechenov First Moscow State Medical University, Moscow, Russia

Babayeva Yu.V.

Sechenov First Moscow State Medical University, Moscow, Russia

Trushenkova V.V.

Sechenov First Moscow State Medical University, Moscow, Russia

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