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Yarovoy S.Yu.

Chazov National Medical Research Center of Cardiology

Shchelkova G.V.

Chazov National Medical Research Center of Cardiology

Dinevich E.O.

Chazov National Medical Research Center of Cardiology

Chazova I.E.

Chazov National Medical Research Center of Cardiology

Boitsov S.A.

Chazov National Medical Research Center of Cardiology

Assessment of adherence to treatment in patients with resistant arterial hypertension according to Russian-language literature. A systematic review

Authors:

Yarovoy S.Yu., Shchelkova G.V., Dinevich E.O., Chazova I.E., Boitsov S.A.

More about the authors

Journal: Russian Cardiology Bulletin. 2025;20(4‑2): 101‑111

DOI: 10.17116/Cardiobulletin202520042101

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Table of contents

ASSESSMENT OF ADHERENCE TO TREATMENT IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION ACCORDING TO RUSSIAN-LANGUAGE LITERATURE. A SYSTEMATIC REVIEW
ASSESSMENT OF ADHERENCE TO TREATMENT IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION ACCORDING TO RUSSIAN-LANGUAGE LITERATURE. A SYSTEMATIC REVIEW

To cite this article:

Yarovoy SYu, Shchelkova GV, Dinevich EO, Chazova IE, Boitsov SA. Assessment of adherence to treatment in patients with resistant arterial hypertension according to Russian-language literature. A systematic review. Russian Cardiology Bulletin. 2025;20(4‑2):101‑111. (In Russ.)
https://doi.org/10.17116/Cardiobulletin202520042101

Подписка 2026 Кардиологический вестник (Russian Cardiology Bulletin)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To study the possibility of assessing the adherence to therapy in patients with resistant hypertension (RH) according to Russian-language literature.

MATERIAL AND METHODS

RH was defined according to clinical guidelines of the Russian Medical Society on Arterial Hypertension (2021). Data were searched in electronic databases and searching engines Google Scholar, eLIBRARY.RU, Central Scientific Medical Library (database inception to 01.12.2023). According to inclusion and exclusion criteria, two independent researchers extracted the articles. Disagreements between researchers were resolved by the third researcher. Study quality was assessed using the Newcastle-Ottawa scale.

RESULTS

Among 1610 primary identified publications, 1473 studies were screened. Finally, the authors assessed 49 full-text articles for eligibility. Four studies were selected for qualitative analysis. There were 256 patients. Adherence was assessed using the Morisky—Green questionnaire in original or modified versions. Analysis revealed significant heterogeneity in results.

DISCUSSION

Objective assessment of adherence to treatment in this disease and development of measures for its improvement are associated with certain difficulties that limits the number of available studies. The authors performed a systematic review and assessed the possibility of structuring and analyzing the information presented in modern Russian-language literature.

CONCLUSION

Most results indicate low adherence among patients that suggests lower real prevalence of RH, as well as reduced effectiveness of treatment due to non-compliance with drug regimen.

Keywords:

treatment adherence
resistant arterial hypertension
pseudoresistance
Morisky—Green scale
antihypertensive therapy

Authors:

Yarovoy S.Yu.

Chazov National Medical Research Center of Cardiology

Shchelkova G.V.

Chazov National Medical Research Center of Cardiology

Dinevich E.O.

Chazov National Medical Research Center of Cardiology

Chazova I.E.

Chazov National Medical Research Center of Cardiology

Boitsov S.A.

Chazov National Medical Research Center of Cardiology

Received:

16.05.2025

Accepted:

04.06.2025

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References:

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