Can McCleery Syndrome Lead to Acute Venous Thrombosis?

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Schastlivtsev I.V.

Pirogov’s Russian National Research Medical University

ORCID: 0000-0002-1306-1502

Lobastov K.V.

Pirogov Russian National Research Medical University

ORCID: 0000-0002-5358-7218

Kanzafarova I.Yu.

Mayo Clinic

Can McCleery Syndrome Lead to Acute Venous Thrombosis?

Authors:

Schastlivtsev I.V., Lobastov K.V., Kanzafarova I.Yu.

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Journal: Journal of Venous Disorders. 2021;15(4): 304‑310

DOI: 10.17116/flebo202115041304

Read: 2559 times

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To cite this article:

Schastlivtsev IV, Lobastov KV, Kanzafarova IYu. Can McCleery Syndrome Lead to Acute Venous Thrombosis? Journal of Venous Disorders. 2021;15(4):304‑310. (In Russ.)
https://doi.org/10.17116/flebo202115041304

Подписка 2026 Флебология (Journal of Venous Disorders)

Использование инфографики авторами научных работ

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Abstract:

Management of McCleery syndrome and its complication are presented. Over 5-year period, the patient periodically suffered from edema and blue discoloration of skin of the right upper extremity arising after physical exertion and regressing at rest after 20-30 min. Thrombosis of the right subclavian vein occurred after physical exercise on December 5, 2017. On December 11, 2017, the patient underwent regional catheter thrombolysis with alteplase (bolus 5 mg followed by infusion 1 mg/100 ml/h). Thrombolytic therapy for 24 hours resulted clinical improvement. Phlebography confirmed complete lysis of clots. However, subclavian vein deformation and parietal filling defect were found within the right costoclavicular space. Ultrasound with functional tests revealed signs of the right subclavian vein compression by anterior scalene muscle. A month later, transient impairment of venous outflow occurred despite anticoagulation. Considering persistent compression by hypertrophied anterior scalene muscle and transient impairment of venous outflow, the patient underwent right-sided scalenotomy on May 23, 2018. Postoperative period was uneventful. Control ultrasound confirmed no compression. Untimely diagnosis of McCleery syndrome and ignorance of its typical symptoms resulted acute thrombosis of the right subclavian vein in this patient. Thrombolysis and anticoagulation ensured complete recanalization of subclavian vein. However, symptoms of periodic positional obstruction of subclavian vein persisted. Scalenotomy eliminated external compression of the right subclavian vein. Surgical treatment not only significantly improved the patient’s quality of life, but also prevented recurrent venous thrombosis.

Keywords:

McCleery syndrome

venous thrombosis

upper extremities

thoracic outlet syndrome

Authors:

Schastlivtsev I.V.

Pirogov’s Russian National Research Medical University

ORCID: 0000-0002-1306-1502

Lobastov K.V.

Pirogov Russian National Research Medical University

ORCID: 0000-0002-5358-7218

Kanzafarova I.Yu.

Mayo Clinic

Received:

28.07.2021

Accepted:

30.08.2021

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References:

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