Thrombolytic therapy of acute massive thromboembolism of the pulmonary artery with the use of recombinant prourokinase

Karpenko A.A.; Starosotskaia M.V.; Cherniavskiĭ M.A.; Cherniavskiĭ A.M.; Belogurov A.A.; Del'ver E.P.

doi:https://doi.org/

Karpenko A.A.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Starosotskaia M.V.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Cherniavskiĭ M.A.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Cherniavskiĭ A.M.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Belogurov A.A.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Del'ver E.P.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Thrombolytic therapy of acute massive thromboembolism of the pulmonary artery with the use of recombinant prourokinase

Authors:

Karpenko A.A., Starosotskaia M.V., Cherniavskiĭ M.A., Cherniavskiĭ A.M., Belogurov A.A., Del'ver E.P.

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Journal: Journal of Venous Disorders. 2010;4(4): 16‑20

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To cite this article:

Karpenko AA, Starosotskaia MV, Cherniavskiĭ MA, Cherniavskiĭ AM, Belogurov AA, Del'ver EP. Thrombolytic therapy of acute massive thromboembolism of the pulmonary artery with the use of recombinant prourokinase. Journal of Venous Disorders. 2010;4(4):16‑20. (In Russ.)

Подписка 2026 Флебология (Journal of Venous Disorders)

Использование инфографики авторами научных работ

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Abstract:

This paper was designed to summarize the experience with the use of purolase, the recombinant urokinase type plasminogen activator, for the treatment of 40 patients presenting with acute massive thromboembolism of the pulmonary artery during the period from 2008 to 2010. The well-apparent dissolution of thrombi, normalization of blood pressure in pulmonary arteries, and stabilization of systemic hemodynamics and gas exchange were documented in 75% of the patients. The results of the study demonstrate the high thromolytic efficacy of purolase and provide a basis for recommending it for the treatment of patients presenting with acute massive thromboembolism of the pulmonary artery.

Keywords:

recombinant prourokinase

purolase

acute thromboembolism of pulmonary arteries

catheter-assisted thrombus fragmentation

thrombolysis

Authors:

Karpenko A.A.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Starosotskaia M.V.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Cherniavskiĭ M.A.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Cherniavskiĭ A.M.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Belogurov A.A.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

Del'ver E.P.

Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina;
Rossiĭskiĭ kardiologicheskiĭ nauchno-proizvodstvennyĭ kompleks Minzdravsotsrazvitiia Rossii, Moskva

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References:

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