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Moskvina L.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Andreeva Yu.Yu.

Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia

Mal'kov P.G.

GUNU "Fakul'tet fundamental'noĭ meditsiny MGU im. M.V. Lomonosova";
GBOU DPO "Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia", Moskva

Frank G.A.

Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena Rosmedtekhnologiĭ, Moskva

New approaches to the classification, grading, and prognosis of renal cell carcinoma

Authors:

Moskvina L.V., Andreeva Yu.Yu., Mal'kov P.G., Frank G.A.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2014;76(2): 60‑70

Read: 12513 times

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NEW APPROACHES TO THE CLASSIFICATION, GRADING, AND PROGNOSIS OF RENAL CELL CARCINOMA
NEW APPROACHES TO THE CLASSIFICATION, GRADING, AND PROGNOSIS OF RENAL CELL CARCINOMA

To cite this article:

Moskvina LV, Andreeva YuYu, Mal'kov PG, Frank GA. New approaches to the classification, grading, and prognosis of renal cell carcinoma. Russian Journal of Archive of Pathology. 2014;76(2):60‑70. (In Russ.)

 
Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Renal cell carcinoma is a heterogeneous group of tumors. Frequent revisions of its histological classification and TNM staging system complicate the retrospective studies of large patient groups and hamper the estimation of survival rates and quality of life for patients. Due to improving therapeutic possibilities, the problems of the staging, morphological diagnosis, grading, and determination of prognostic factors of renal cell carcinomas have assumed a particular significance. Despite the long-term history of studies dealing with renal cell carcinoma, there is no general agreement among specialists at to these issues. The paper reviews the recent International Society of Urological Pathology Consensus held in Vancouver in March 2013.

Keywords:

renal cell carcinoma
classification
grading
prognosis

Authors:

Moskvina L.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Andreeva Yu.Yu.

Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia

Mal'kov P.G.

GUNU "Fakul'tet fundamental'noĭ meditsiny MGU im. M.V. Lomonosova";
GBOU DPO "Rossiĭskaia meditsinskaia akademiia poslediplomnogo obrazovaniia", Moskva

Frank G.A.

Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena Rosmedtekhnologiĭ, Moskva

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References:

  1. Eble J.N., Sauter G., Epstein J.I., Sesterhenn I.A. Tumors of the system and male genital organs. Lyon, France: IARC Press; 2004. 324 p.
  2. Srigley J.R., Delahunt B., Eble J.N. et al. ISUP Renal Tumor Panel. The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. Am. J. Surg. Pathol. 2013; 37 (10): 1469-89.
  3. Mazzucchelli R., Scarpelli M., Montironi R., Cheng L. et al. Multilocular cystic renal cell neoplasms of low malignant potential. Anal. Quant. Cytol. Histol. 2012; 34 (5): 235-8.
  4. Gunia S., Erbersdobler A., Koch S., Otto W. et al. Protein gene product 9.5 is diagnostically helpful in delineating high-grade renal cell cancer involving the renal medullary/sinus region from invasive urothelial cell carcinoma of the renal pelvis. Hum. Pathol. 2013; 44 (5): 712-7.
  5. Carrión López P., Martínez Ruiz J., Fernández Anguita P.J., Martínez Sanchiz C. et al. Tubulocystic renal carcinoma (low grade collecting duct carcinoma). Arch. Esp. Urol. 2012; 65 (9): 841-4.
  6. Srigley J.R., Delahunt B. Uncommon and recently described renal carcinomas. Mod. Pathol. 2009; 22: 2-23.
  7. Yang X.J., Zhou M., Hes O., Shen S. et al. Tubulocystic carcinoma of the kidney: clinicopathologic and molecular characterization. Am. J. Surg. Pathol. 2008; 32 (2): 177-87.
  8. Amin M.B., MacLennan G.T., Gupta R., Grignon D. et al. Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma. Am. J. Surg. Pathol. 2009; 33 (3): 384-92.
  9. Ahn S., Kwon G.Y., Cho Y.M., Jun S.Y. et al. Acquired cystic disease-associated renal cell carcinoma: further characterization of the morphologic and immunopathologic features. Med. Mol. Morphol. 2013; 46 (4): 225-32.
  10. Kuroda N., Yamashita M., Kakehi Y., Hes O. et al. Acquired cystic disease-associated renal cell carcinoma: an immunohistochemical and fluorescence in situ hybridization study. Med. Mol. Morphol. 2011; 44 (4): 228-32.
  11. Aydin H., Chen L., Cheng L., Vaziri S. et al. Clear cell tubulopapillary renal cell carcinoma: a study of 36 distinctive low-grade epithelial tumors of the kidney. Am. J. Surg. Pathol. 2010; 34 (11): 1608-21.
  12. Rohan S.M., Xiao Y., Liang Y., Dudas M.E. et al. Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins. Mod. Pathol. 2011; 24 (9): 1207-20.
  13. Wolfe A., Dobin S.M., Grossmann P., Michal M. et al. Clonal trisomies 7,10 and 12, normal 3p and absence of VHL gene mutation in a clear cell tubulopapillary carcinoma of the kidney. Virchows. Arch. 2011; 459 (4): 457-63.
  14. Sukov W.R., Hodge J.C., Lohse C.M., Akre M.K. et al. ALK alterations in adult renal cell carcinoma: frequency, clinicopathologic features and outcome in a large series of consecutively treated patients. Mod. Pathol. 2012; 25 (11): 1516-25.
  15. Brimo F., Robinson B., Guo C., Zhou M. et al. Renal epithelioid angiomyolipoma with atypia: a series of 40 cases with emphasis on clinicopathologic prognostic indicators of malignancy. Am. J. Surg. Pathol. 2010; 34 (5): 715-22.
  16. Srigley J.R., Delahunt B., Eble J.N. et al. ISUP Renal Tumor Panel. The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. Am. J. Surg. Pathol. 2013;37 (10): 1469-89.
  17. Wilkinson C., Palit V., Bardapure M., Thomas J. et al. Adult multilocular cystic nephroma: Report of six cases with clinical, radio-pathologic correlation and review of literature. Urol. Ann. 2013; 5 (1): 13-7.
  18. Delahunt B. Advances and controversies in grading and staging of renal cell carcinoma Mod. Pathol. 2009; 22: 24-36.
  19. Cheville J.C., Lohse C.M., Sukov W.R., Thompson R.H., et al. Chromophobe renal cell carcinoma: the impact of tumor grade on outcome. Am. J. Surg. Pathol. 2012; 36 (6): 851-6.
  20. Zigeuner R., Hutterer G., Chromecki T., Imamovic A. et al. External validation of the Mayo Clinic stage, size, grade, and necrosis (SSIGN) score for clear-cell renal cell carcinoma in a single European centre applying routine pathology. Eur. Urol. 2010; 57 (1): 102-9.
  21. Christine M., Lohse M., Michael L. Blute, M.D. et al. Comparison of standardized and nonstandardized nuclear grade of renal cell carcinoma to predict outcome among 2,042 patients. Am. J. Clin. Pathol. 2002; 118 (6): 312-21.
  22. Delahunt B., Sika-Paotonu D., Bethwaite P.B., William Jordan T. et al. Grading of clear cell renal cell carcinoma should be based on nucleolar prominence. Am. J. Surg. Pathol. 2011; 35 (8): 1134-9.
  23. Lee W.K., Byun S.S., Kim H.H., Rha K.H. et al. Characteristics and prognosis of chromophobe non-metastatic renal cell carcinoma: a multicenter study. Int. J. Urol. 2010; 17 (11): 898-904.
  24. Delahunt B., Cheville J.C., Martignoni G., Members of the ISUP Renal Tumor Panel. The International Society of Urological Pathology (ISUP) grading system for renal cell carcinoma and other prognostic parameters. Am. J. Surg. Pathol. 2013; 37 (10): 1490-504.
  25. Leroy X., Zini L., Buob D., Ballereau C. et al. Renal cell carcinoma with rhabdoid features: an aggressive neoplasm with overexpression of p53. Arch. Pathol. Lab. Med. 2007; 131 (1): 102-6.
  26. Trpkov K., Grignon D.J., Bonsib S.M. et al.; members of the ISUP Renal Tumor Panel. Handling and staging of renal cell carcinoma: the International Society of Urological Pathology Consensus (ISUP) conference recommendations. Am. J. Surg. Pathol. 2013; 37 (10): 1505-17.
  27. Tan P.H., Cheng L., Rioux-Leclercq N., ISUP Renal Tumor Panel. Renal tumors: diagnostic and prognostic biomarkers. Am. J. Surg. Pathol. 2013; 37 (10): 1518-31.
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