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Efremova Iu.E.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

Andreeva E.R.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

Soboleva G.N.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

Radiukhina N.V.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

Beloyartsev D.F.

Vishnevskiy Surgery Institute, Moscow

Karpov Iu.A.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

Tararak É.M.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

In vitro accumulation of the photosensitizer Photosens in the atherosclerotic plaque of the human carotid artery

Authors:

Efremova Iu.E., Andreeva E.R., Soboleva G.N., Radiukhina N.V., Beloyartsev D.F., Karpov Iu.A., Tararak É.M.

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Journal: Russian Journal of Archive of Pathology. 2012;74(5): 18‑22

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Table of contents

IN VITRO ACCUMULATION OF THE PHOTOSENSITIZER PHOTOSENS IN THE ATHEROSCLEROTIC PLAQUE OF THE HUMAN CAROTID ARTERY
IN VITRO ACCUMULATION OF THE PHOTOSENSITIZER PHOTOSENS IN THE ATHEROSCLEROTIC PLAQUE OF THE HUMAN CAROTID ARTERY

To cite this article:

Efremova IuE, Andreeva ER, Soboleva GN, Radiukhina NV, Beloyartsev DF, Karpov IuA, Tararak ÉM. In vitro accumulation of the photosensitizer Photosens in the atherosclerotic plaque of the human carotid artery. Russian Journal of Archive of Pathology. 2012;74(5):18‑22. (In Russ.)

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The investigation was undertaken to study the accumulation of the photosensitizer Photosens in arterial atherosclerotic plaques and to immunohistochemically identify cellular elements in them. Specimens were obtained during carotid endarterectomy. The preferential accumulation of Photosens occurred in the plaque areas containing the largest number of cells, such as macrophages and lymphocytes. The photosensitizer accumulated to a greater extent in the unstable plaques than in the stable ones, which seems to be associated with the more marked infiltration of unstable plaques by the cells involved in the inflammatory reaction.

Keywords:

atherosclerosis
carotid artery
photodynamic reaction

Authors:

Efremova Iu.E.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

Andreeva E.R.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

Soboleva G.N.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

Radiukhina N.V.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

Beloyartsev D.F.

Vishnevskiy Surgery Institute, Moscow

Karpov Iu.A.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

Tararak É.M.

Laboratoriia molekuliarnoĭ i kletochnoĭ kardiologii i otdel angiologii Rossiĭskogo kardiologicheskogo nauchno-proizvodstvennogo kompleksa Minzdravsotsrazvitiia Rossii

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References:

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