Symptoms of dissociation and disconnection in patients with disorders of consciousness

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The authors present methodological approaches to analysis of neurological symptoms and dysregulation of various functions in patients with chronic disorders of consciousness based on comprehensive assessment with allocation of symptoms of dissociation and disconnection. This can improve accuracy of prognosis and outcomes. Importantly, the concept of allostasis is applicable to these patients. Clinical manifestations of allostasis are paroxysmal sympathetic hyperactivity and systemic inflammatory reaction.

Keywords:

chronic disorders of consciousness

vegetative state

unresponsive wakefulness syndrome

minimally conscious state

allostasis

cognitive-motor dissociation

dissociation

sympathetic hyperactivity

circadian rhythms

Authors:

Kondratieva E.A.

Polenov Neurosurgical Institute branch of Almazov National Medical Research Centre

Likhterman L.B.

Burdenko Neurosurgical Center

Zakharova N.E.

Burdenko Neurosurgical Center

Ivanova N.E.

Polenov Russian Scientific Research Neurosurgical Institute — branch of Almazov National Medical Research Center

Kondratiev A.N.

Polenov Neurosurgical Institute

SPIN RSCI: 8235-9765
ORCID: 0000-0002-7648-2208

Received:

07.06.2022

Accepted:

04.08.2022

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