Objective — to determine diagnostic significance of native test of thromboelastometry for liver resections with colorectal cancer metastases. Material and methods. There were 25 patients who underwent liver resection for colorectal cancer metastases. Coagulation tests including international normalized ratio (INR), activated partial thromboplastin time (APTT), fibrinogen and D-dimer level, platelet count were performed prior to surgery, at the end of surgical intervention and on the next postoperative day. In parallel, thromboelastometry tests were performed (EXTEM, INTEM, NATEM) in order to evaluate CT, CFT, alpha angle, MCF. Results. CT EXTEM, INTEM intervals were normal. CT NATEM was reduced in 51.7% of cases, no elongation was observed. An increase of INR >1.5 was found in 38% of cases, APTT augmentation (>1.5 times) was noted only in one case. Direct moderate correlation was detected only between CT Extem and INR. There was a correlation between APTT and CT INTEM, NATEM in preoperative period. CFT EXTEM, INTEM intervals were within normal values, except cases of severe thrombocytopenia (n=5). Shortening of CFT NATEM was revealed in 72% of cases, no elongation was observed. The association of CFT NATEM interval with fibrinogen level and platelet count was much weaker than in similar EXTEM and INTEM values. Strong correlation was found between MCF values in NATEM, EXTEM and INTEM tests. The correlation between fibrinogen level, platelet count and MCF values was similar in various tests. Conclusion. Reduced CT and CFT intervals in native test of TEM correlates with prothrombotic changes in hemostatic system that is typical for cancer patients. NATEM may be used to assess coagulation system along with other tests of thromboelastometry.