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Kvan O.K.

Burdenko Neurosurgical Center

Teryaeva N.B.

Burdenko Neurosurgical Center

Sukhorukova M.V.

Burdenko Neurosurgical Center

Lubnin A.Yu.

Burdenko Neurosurgical Center

Bacterial contamination of autologous blood in reinfusion in neurosurgery: a phenomenon or a problem?

Authors:

Kvan O.K., Teryaeva N.B., Sukhorukova M.V., Lubnin A.Yu.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2024;88(2): 54‑61

DOI: 10.17116/neiro20248802154

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To cite this article:

Kvan OK, Teryaeva NB, Sukhorukova MV, Lubnin AYu. Bacterial contamination of autologous blood in reinfusion in neurosurgery: a phenomenon or a problem?. Burdenko's Journal of Neurosurgery. 2024;88(2):54‑61. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20248802154

Подписка 2025 (Burdenko's Journal of Neurosurgery)
 
 
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There is a problem of bacterial contamination of autologous blood despite long-term experience of intraoperative blood salvage and reinfusion.

OBJECTIVE

To analyze safety of blood reinfusion with white blood cell filtration and X-ray irradiation for blood decontamination in neurosurgery.

MATERIAL AND METHODS

The study included 57 patients with various neurosurgical diseases. We used intraoperative blood reinfusion in all patients considering high predictable risk of major blood loss due to neurosurgical diseases, features of neoplasm topography, anamnesis and examination data. Microbiological examination of autologous blood was carried out at different stages before reinfusion.

RESULTS

Bacterial contamination of autologous blood samples was observed in 42% of patients. Enlargement of surgical access to paranasal sinuses in patients with craniofacial lesions poses a potential risk of bacterial contamination of autologous blood. Additional methods of decontamination including white blood cell filtration and X-ray irradiation reduced bacterial load. The above-mentioned methods were less effective for decontamination of microflora not typical for human skin compared to saprophytic ones. There were no postoperative infectious complications.

CONCLUSION

Combination of white blood cell filtration and X-ray irradiation reduces bacterial contamination and increases safety of reinfusion although these methods do not completely free autologous blood from opportunistic microorganisms. Decontamination quality significantly depended on microflora and surgical approach.

Keywords:

blood reinfusion
problems of bacterial contamination
autologous blood
surgical access
endoscopic endonasal surgery

Authors:

Kvan O.K.

Burdenko Neurosurgical Center

Teryaeva N.B.

Burdenko Neurosurgical Center

Sukhorukova M.V.

Burdenko Neurosurgical Center

Lubnin A.Yu.

Burdenko Neurosurgical Center

Received:

06.12.2023

Accepted:

12.01.2024

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