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Makashova E.S.
Burdenko Neurosurgical Center;
Loginov Moscow Clinical Scientific Practical Center
Galkin M.V.
Burdenko National Medical Research Center for Neurosurgery
Molecular genetic features of meningiomas
Journal: Burdenko's Journal of Neurosurgery. 2023;87(4): 101‑106
Views: 1626
Downloaded: 56
To cite this article:
Makashova ES, Lasunin NV, Galkin MV, Zolotova SV, Karandasheva KO, Golanov AV. Molecular genetic features of meningiomas. Burdenko's Journal of Neurosurgery.
2023;87(4):101‑106. (In Russ., In Engl.)
https://doi.org/10.17116/neiro202387041101
Meningioma is the most common primary tumor of the central nervous system. Traditional classification is based on histological properties of tumors and distinguishes different grades of meningioma malignancy. However, knowledge about different molecular mechanisms of tumor provided new data on genetic features of meningiomas. The authors analyze current available data on the main driver mutations, new classifications based on molecular genetic characteristics and potential targets for therapy.
Keywords:
Authors:
Makashova E.S.
Burdenko Neurosurgical Center;
Loginov Moscow Clinical Scientific Practical Center
Galkin M.V.
Burdenko National Medical Research Center for Neurosurgery
Received:
01.12.2022
Accepted:
19.05.2023
List of references:
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