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Guzeva V.I.

Saint Petersburg State Pediatric Medical University

Kutsev S.I.

Research Center for Medical Genetics named after Academician N.P. Bochkov

Petrukhin A.S.

Pirogov Russian National Research Medical University

Ayvazyan S.O.

LLC «Center of Epileptology and Neurology Neurogenesis»;
Voino-Yasenetskiy Research-Practical Center of Children Specialized Medical Care

Belousova E.D.

Research Clinical Institute of Pediatric of Pirogov Russian National Research Medical University

Burd S.G.

Pirogov Russian National Research Medical University

Volkov I.V.

LLC «Sibneuromed»

Globa O.V.

National Medical Research Center for Children’s Health

Dorofeeva M.Yu.

Veltishchev Research and Clinical Institute for Pediatrics and Pediatric Surgery

Ermolenko N.A.

Burdenko Voronezh State Medical University

Morozova E.A.

Kazan State Medical Academy

Rakhmanina O.A.

Tumen State Medical University

Sparber P.A.

Research Center for Medical Genetics named after Academician N.P. Bochkov

Sosnina I.B.

Saint Petersburg State Budgetary Healthcare Institution «Consultative and Diagnostic Center for Children»

Tomenko T.R.

Ural Federal University named after the first President of Russia B.N. Yeltsin;
LLC «European Medical Center UGMK-Zdorovie»

Usacheva E.L.

Russian Children Clinical Hospital — branch of Pirogov National Research Medical University

Tsotsonava Zh.M.

Astrakhan State Medical University

Shestakova O.I.

Omsk State Medical University

Modern approaches to the diagnosis and treatment of Dravet syndrome in the Russian Federation. (Literature review and resolution of the Expert Council)

Authors:

Guzeva V.I., Kutsev S.I., Petrukhin A.S., Ayvazyan S.O., Belousova E.D., Burd S.G., Volkov I.V., Globa O.V., Dorofeeva M.Yu., Ermolenko N.A., Morozova E.A., Rakhmanina O.A., Sparber P.A., Sosnina I.B., Tomenko T.R., Usacheva E.L., Tsotsonava Zh.M., Shestakova O.I.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(9): 103‑116

DOI: 10.17116/jnevro2025125091103

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Table of contents

MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT OF DRAVET SYNDROME IN THE RUSSIAN FEDERATION. (LITERATURE REVIEW AND RESOLUTION OF THE EXPERT COUNCIL)
MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT OF DRAVET SYNDROME IN THE RUSSIAN FEDERATION. (LITERATURE REVIEW AND RESOLUTION OF THE EXPERT COUNCIL)

To cite this article:

Guzeva VI, Kutsev SI, Petrukhin AS, et al. . Modern approaches to the diagnosis and treatment of Dravet syndrome in the Russian Federation. (Literature review and resolution of the Expert Council). S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(9):103‑116. (In Russ.)
https://doi.org/10.17116/jnevro2025125091103

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Abstract:

Dravet syndrome (DS) is a rare genetic disorder with onset at 1 year of age, one of the most severe forms of epilepsy, which is characterized by a high frequency and severity of seizures, impaired psychoneurological development, disability and high mortality. Timely diagnosis and treatment can significantly alleviate the course of DS and improve the quality of life of patients and their families. Currently, there is an urgent need to increase awareness of pediatric neurologists and primary care physicians about the diagnostic criteria for the timely detection of patients with DS, referral to an epileptologist to confirm the diagnosis and prescribe the necessary therapy. The provisions of the Expert Council’s resolution, which took place on March 14, 2025, are presented.

Keywords:

epileptic syndromes
Dravet syndrome
SCN1A
stiripentol

Authors:

Guzeva V.I.

Saint Petersburg State Pediatric Medical University

Kutsev S.I.

Research Center for Medical Genetics named after Academician N.P. Bochkov

Petrukhin A.S.

Pirogov Russian National Research Medical University

Ayvazyan S.O.

LLC «Center of Epileptology and Neurology Neurogenesis»;
Voino-Yasenetskiy Research-Practical Center of Children Specialized Medical Care

Belousova E.D.

Research Clinical Institute of Pediatric of Pirogov Russian National Research Medical University

Burd S.G.

Pirogov Russian National Research Medical University

Volkov I.V.

LLC «Sibneuromed»

Globa O.V.

National Medical Research Center for Children’s Health

Dorofeeva M.Yu.

Veltishchev Research and Clinical Institute for Pediatrics and Pediatric Surgery

Ermolenko N.A.

Burdenko Voronezh State Medical University

Morozova E.A.

Kazan State Medical Academy

Rakhmanina O.A.

Tumen State Medical University

Sparber P.A.

Research Center for Medical Genetics named after Academician N.P. Bochkov

Sosnina I.B.

Saint Petersburg State Budgetary Healthcare Institution «Consultative and Diagnostic Center for Children»

Tomenko T.R.

Ural Federal University named after the first President of Russia B.N. Yeltsin;
LLC «European Medical Center UGMK-Zdorovie»

Usacheva E.L.

Russian Children Clinical Hospital — branch of Pirogov National Research Medical University

Tsotsonava Zh.M.

Astrakhan State Medical University

Shestakova O.I.

Omsk State Medical University

Received:

27.08.2025

Accepted:

09.09.2025

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