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Zaharova V.V.

Privolzhsky Research Medical University

Ruina E.A.

Privolzhsky Research Medical University

Antipenko E.A.

Privolzhsky Research Medical University

Stiff-person syndrome

Authors:

Zaharova V.V., Ruina E.A., Antipenko E.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(6): 139‑144

DOI: 10.17116/jnevro2024124061139

Read: 1457 times

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Table of contents

STIFF-PERSON SYNDROME
STIFF-PERSON SYNDROME

To cite this article:

Zaharova VV, Ruina EA, Antipenko EA. Stiff-person syndrome. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;124(6):139‑144. (In Russ.)
https://doi.org/10.17116/jnevro2024124061139

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Recommended articles:
The difficulties with diagnostics of the stiff man syndrome. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(10):92-96
Abstract:

Stiff-person syndrome is a rare autoimmune disorder manifested by stiffness in the trunk and proximal limb muscles and painful muscle spasms in them. The disease is associated with the production of glutamate decarboxylase autoantibodies, an enzyme converting glutamate into gamma-aminobutyric acid. An increase of anti-GAD antibody serum levels above 10.000 IU/mL is specific for stiff-person syndrome. Our own clinical observation of a patient diagnosed with stiff-person syndrome is presented.

Keywords:

stiff-person syndrome
glutamate decarboxylase autoantibodies
anti-GAD antibody

Authors:

Zaharova V.V.

Privolzhsky Research Medical University

Ruina E.A.

Privolzhsky Research Medical University

Antipenko E.A.

Privolzhsky Research Medical University

Received:

29.01.2024

Accepted:

03.02.2024

Close metadata

References:

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