Experience of staged and simultaneous bilateral thalamotomy using MR-guided focused ultrasound in the treatment of essential tremor

Nabiullina DI, Galimova RM, Illarioshkin SN, et al. . Experience of staged and simultaneous bilateral thalamotomy using MR-guided focused ultrasound in the treatment of essential tremor. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(7):65‑73. (In Russ.)
https://doi.org/10.17116/jnevro202312307165

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry)

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OBJECTIVE

To show that effective and safe bilateral MR-guided focused ultrasound (MRgFUS) treatment of essential tremor (ET) is achievable.

MATERIAL AND METHODS

Four male patients underwent bilateral thalamotomy. Two patients underwent staged thalamotomy, with the ≥12 month interval between operations. Two patients underwent simultaneous bilateral thalamotomy.

RESULTS

After six months, all patients noted a significant reduction in symptoms on both sides: when assessing tremors with the Clinical Rating Scale for Tremor, the severity of hyperkinesis decreased by 57.5—69.7%. We did not observe any complications in any of the cases.

CONCLUSION

Our experience indicates that simultaneous bilateral MRI-guided focused ultrasound treatment of ET can be performed safely and effectively. Further research is necessary to estimate the effectiveness and adverse effect rates.

Keywords:

MR-guided focused ultrasound

essential tremor

VIM thalamotomy

bilateral staged and simultaneous operations

Authors:

Nabiullina D.I.

Buzaev Clinics of Intellectual Neurosurgery the International Medical Center

ORCID: 0000-0003-2570-3709

Galimova R.M.

Buzaev Clinics of Intellectual Neurosurgery the International Medical Center;
Bashkir State Medical University

ORCID: 0000-0003-2758-0351

Illarioshkin S.N.

Research Center of Neurology

SPIN RSCI: 8646-9426
Scopus AuthorID: 7004025426
ResearcherID: C-9033-2012
ORCID: 0000-0002-2704-6282

Buzaev I.V.

Buzaev Clinics of Intellectual Neurosurgery the International Medical Center;
Bashkir State Medical University

ORCID: 0000-0003-0511-9345

Safin Sh.M.

Bashkir State Medical University

ORCID: 0000-0002-0100-6100

Akhmadeeva G.N.

Buzaev Clinics of Intellectual Neurosurgery the International Medical Center

ORCID: 0000-0001-5516-0587

Mukhamadeeva N.R.

Buzaev Clinics of Intellectual Neurosurgery the International Medical Center

ORCID: 0000-0001-5158-2707

Krekotin D.K.

Buzaev Clinics of Intellectual Neurosurgery the International Medical Center

ORCID: 0000-0002-2215-7178

Received:

27.02.2023

Accepted:

16.04.2023

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