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Kucherenko S.S.

Almazov National Medical Research Center;
Sokolov North-Western District Scientific and Clinical Center

Alekseeva T.M.

Almazov National Medical Research Center

Modern strategies of antithrombotic therapy in patients with multifocal atherosclerosis

Authors:

Kucherenko S.S., Alekseeva T.M.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(2): 49‑55

DOI: 10.17116/jnevro202212202149

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Table of contents

MODERN STRATEGIES OF ANTITHROMBOTIC THERAPY IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS
MODERN STRATEGIES OF ANTITHROMBOTIC THERAPY IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS

To cite this article:

Kucherenko SS, Alekseeva TM. Modern strategies of antithrombotic therapy in patients with multifocal atherosclerosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(2):49‑55. (In Russ.)
https://doi.org/10.17116/jnevro202212202149

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
 
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Abstract:

The manuscript is devoted to the problem of selection of antithrombotic therapy in the management of patients with multifocal atherosclerosis. The leading role of cerebrovascular pathology in the structure of mortality and causes of disability is noted. The questions of etiology and pathogenesis of acute cerebrovascular accident are considered. The pathogenetic subtypes of ischemic stroke and the criteria for their diagnosis were analyzed. The important role of antithrombotic therapy in the prevention of noncardioembolic stroke is presented. Considering the evidence-based medicine data based on the analysis of randomized trials results, modern strategies of antithrombotic therapy were demonstrated. A comparative analysis of the clinical trials results was carried out. New ideas about the benefits of combination therapy with acetylsalicylic acid at a dose of 100 mg/day and with rivaroxaban 2.5 mg twice daily, established in the COMPASS study, are presented.

Keywords:

multifocal atherosclerosis
antithrombotic therapy
prevention of noncardioembolic ischemic stroke

Authors:

Kucherenko S.S.

Almazov National Medical Research Center;
Sokolov North-Western District Scientific and Clinical Center

Alekseeva T.M.

Almazov National Medical Research Center

Received:

21.12.2021

Accepted:

17.01.2022

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