Treatment of chronic cerebral venous insufficiency: a study on an effect of L-lysine aescinat

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Chukanova E.I.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Moskva

Mamayeva Kh.I.

Pirogov Russian National Research Medical University, Moscow

Chukanova A.S.

Treatment of chronic cerebral venous insufficiency: a study on an effect of L-lysine aescinat

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Chukanova E.I., Mamayeva Kh.I., Chukanova A.S.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(7): 37‑41

DOI: 10.17116/jnevro20161167137-41

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To cite this article:

Chukanova EI, Mamayeva KhI, Chukanova AS. Treatment of chronic cerebral venous insufficiency: a study on an effect of L-lysine aescinat. S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(7):37‑41. (In Russ.)
https://doi.org/10.17116/jnevro20161167137-41

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Objective: To study an effect of L-lysine aescinat on the dynamics of complaints, severity of neurological syndromes and parameters of cerebral blood flow estimated by transcranial doppler and duplex scanning in patients with chronic cerebral venous insufficiency (CCVI). Material and methods: Eighty patients with ultrasound-confirmed CCVI were examined. The basic group included 40 patients who received two treatment courses (intravenous drop-by-drop/stream introductions of L-lysine aescinat in the dose of 5ml during 7 days in 2nd and 30th days of examination). The comparison group consisted of 40 patients. Results and Conclusion: Treatment with L-lysine aescinat led to the significant decrease in complaints and improved the scores on the scales used in the study. There was an improvement in the cerebral hemodynamics (an increase of hemodynamic reserve and normalization of the linear blood flow velocity in deep veins) in the patients with CCVI. The safe profile of L-lysine aescinat used in recommended doses was confirmed.

Keywords:

chronic cerebral venous insufficiency

L-lysine aescinat

dehydratation

prothrombotic conditions

venous drainage system

Authors:

Chukanova E.I.

Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Moskva

Mamayeva Kh.I.

Pirogov Russian National Research Medical University, Moscow

Chukanova A.S.

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