Frontotemporal degeneration: a clinical case and experience of using of diffusion tensor magnetic-resonance imaging tractography

Kulesh A.A.; Drobakha V.E.; Shestakov V.V.; Lapaeva T.V.; Dementyeva O.V.

doi:https://doi.org/10.17116/jnevro2015115111112-116

Kulesh A.A.

Permskaia gosudarstvennaia meditsinskaia akademiia im. akad. E.A. Vagnera

Drobakha V.E.

Vagner Perm Medical University, Perm, Russia

Shestakov V.V.

Permskaia gosudarstvennaia meditsinskaia akademiia

Lapaeva T.V.

GBOU VPO "Permskaia gosudarstvennaia meditsinskaia akademiia im. akad. E.A. Vagnera", Perm'

Dementyeva O.V.

Wagner Perm State Medical University, Perm

Frontotemporal degeneration: a clinical case and experience of using of diffusion tensor magnetic-resonance imaging tractography

Authors:

Kulesh A.A., Drobakha V.E., Shestakov V.V., Lapaeva T.V., Dementyeva O.V.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2015;115(11): 112‑116

DOI: 10.17116/jnevro2015115111112-116

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To cite this article:

Kulesh AA, Drobakha VE, Shestakov VV, Lapaeva TV, Dementyeva OV. Frontotemporal degeneration: a clinical case and experience of using of diffusion tensor magnetic-resonance imaging tractography. S.S. Korsakov Journal of Neurology and Psychiatry. 2015;115(11):112‑116. (In Russ.)
https://doi.org/10.17116/jnevro2015115111112-116

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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Abstract:

Frontotemporal degeneration is a frequent cause of presenile dementia that makes up from 5 to 17% of autopsy-confirmed cases developed at the age of 70 years. Authors report a case of this disease, discuss the possible causes of its development and present the results of diffusion tensor magnetic resonance tractography. Clinical features of this case are practically isolated speech disturbance with the most likely domination of a semantic variant of primary progressive aphasia. Magnetic-resonance imaging has an important practical significance for this pathology due to the possibility of assessing atrophic zones. The use of DTI-tractography allows to extend diagnostic possibilities.

Keywords:

frontotemporal degeneration

semantic dementia

DTI

tractography