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Putilina M.V.

Kafedra nevrologii fakulteta usovershenstvovaniia vracheĭ Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Grishin D.V.

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Putilina M.V., Grishin D.V.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(11): 29‑34

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To cite this article:

Putilina MV, Grishin DV. . S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(11):29‑34. (In Russ.)

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Fifty patients with cervical dorsopathy with the vertebral artery syndrome were studied using clinical scales (neurological deficit, psychoemotional disturbances) and laboratory methods (parameters of oxidant stress). The correlations between the oxidant stress and the dynamics of neurological syndromes and psychoemotional disturbances as well as the efficacy and safety of their treatment with antioxidants (mexiprim) were determined.

Authors:

Putilina M.V.

Kafedra nevrologii fakulteta usovershenstvovaniia vracheĭ Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Grishin D.V.

List of references:

  1. Antigipoksanty i aktoprotektory: itogi i perspektivy. St-Peterburg: Terra 1994; 132.
  2. Bobyrev V.N., Vesel'skii I.Sh., Bobyreva L.E. Antioksidanty v profilaktike i terapii tserebral'nogo ateroskleroza. Zhurn nevrol i psikhiat 1989; 9: 60-63.
  3. Boldyrev M.Yu., Maksimova M.Yu., Suslina Z.A. Molekulyarnye mekhanizmy okislitel'nogo stressa v mozge i strategiya antioksidantnoi terapii. M 2001.
  4. Vladimirov Yu.A. Svobodnye radikaly v pervichnykh fotobiologicheskikh protsessakh. Biol membrany 1998; 5: 517-529.
  5. Voronina T.A. Mekhanizm deistviya i obosnovanie primeneniya preparata meksidol v nevrologii. Materialy nauchno-prakticheskoi konferentsii po nevrologii. M 2000; 14-16.
  6. Gusev E.I., Skvortsova V.I. Ishemiya golovnogo mozga. M: Meditsina 2001; 328.
  7. Zavalishin I.A., Zakharova M.N. Oksidantnyi stress - obshchii mekhanizm povrezhdeniya pri zabolevaniyakh nervnoi sistemy. Zhurn nevropatol i psikhiat 1996; 2: 2: 111-114.
  8. Ivnitskii Yu.Yu. Yantarnaya kislota v sisteme metabolicheskoi korrektsii funktsional'nogo sostoyaniya i rezistentnosti organizma. St-Peterburg 1998; 82.
  9. Putilina M.V., Grishin D.V. Rol' oksidantnogo stressa v patogeneze dorsopatii. Vozmozhnosti korrektsii negativnykh posledstvii. Vrach 2009; 12: 9-13.
  10. Putilina M.V., Grishin D.V. Sindrom pozvonochnoi arterii: diagnostika i terapiya. Farmateka 2010; 20: 84-90.
  11. Putilina M.V. Sovremennye predstavleniya o terapii trevozhno-depressivnykh rasstroistv pri khronicheskoi ishemii golovnogo mozga. RMZh 2011; 19: 2: 1-6.
  12. Fedin A.I. Oksidantnyi stress i primenenie antioksidantov v nevrologii. Atmosfera. Nervnye bolezni 2002; 1: 15-18.
  13. Fedin A.I. Dorsopatii (klassifikatsiya i diagnostika). Atmosfera. Nervnye bolezni 2002; 2: 2-12.
  14. Aust S.D., Svingen B.A. The role of iron in enzymatic lipid peroxidation. Free Radicals in Biol 1982; 5: 1-28.
  15. Cebbolos-Picot I. The role of oxidative stress in Neuronal Death. Springer 1997; 203.

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