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Romanova G.A.

NII obshcheĭ patologii i patofiziologii RAMN

Shakova F.M.

NII obshcheĭ patologii i patofiziologii RAMN

Barskov I.V.

NTs nevrologii RAMN

Stel'mashuk E.V.

NTs nevrologii RAMN

Petrov T.V.

ZAO «Farm-Sintez», Moskva

Sokolov M.A.

ZAO «Farm-Sintez», Moskva

Effect of celleks on functional and morphological changes in experimental focal ischemia of prefrontal areas of the rat brain cortex

Authors:

Romanova G.A., Shakova F.M., Barskov I.V., Stel'mashuk E.V., Petrov T.V., Sokolov M.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(9‑2): 52‑56

Read: 1620 times

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Table of contents

EFFECT OF CELLEKS ON FUNCTIONAL AND MORPHOLOGICAL CHANGES IN EXPERIMENTAL FOCAL ISCHEMIA OF PREFRONTAL AREAS OF THE RAT BRAIN CORTEX
EFFECT OF CELLEKS ON FUNCTIONAL AND MORPHOLOGICAL CHANGES IN EXPERIMENTAL FOCAL ISCHEMIA OF PREFRONTAL AREAS OF THE RAT BRAIN CORTEX

To cite this article:

Romanova GA, Shakova FM, Barskov IV, Stel'mashuk EV, Petrov TV, Sokolov MA. Effect of celleks on functional and morphological changes in experimental focal ischemia of prefrontal areas of the rat brain cortex. S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(9‑2):52‑56. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

The effect of the new original drug celleks on the functional CNS activity and volume of ischemic damage has been studied in the experimental model of photochemically induced bilateral thrombosis of the prefrontal cortex. The chronic (once a day during 4 days) and even single (one hour after the operation) treatment of rats with celleks (intraperitoneal, 3 mg/kg) after the cortical photothrombosis resulted in the restoration of passive avoidance and diminishing of the volume of ischemic damage.

Keywords:

rats
focal ischemia of prefrontal areas of brain cortex
passive avoidance response
volume of ischemic infarction
celleks

Authors:

Romanova G.A.

NII obshcheĭ patologii i patofiziologii RAMN

Shakova F.M.

NII obshcheĭ patologii i patofiziologii RAMN

Barskov I.V.

NTs nevrologii RAMN

Stel'mashuk E.V.

NTs nevrologii RAMN

Petrov T.V.

ZAO «Farm-Sintez», Moskva

Sokolov M.A.

ZAO «Farm-Sintez», Moskva

Close metadata

References:

  1. Gusev E.I., Skvortsova V.I. Ishemiya golovnogo mozga. M: Meditsina 2001; 328.
  2. Watson B.D., Dietrich W.D., Busto R. et al. Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol 1985; 17: 5: 497-504.
  3. Romanova G.A., Silachev D.N., Shakova F.M. i dr. Neiroprotektivnoe i antiamnesticheskoe deistvie peptida semaksa pri eksperimental'nom ishemicheskom infarkte kory golovnogo mozga. Byul eksper biol i med 2006; 142: 12: 618-621.
  4. Silachev D.N., Shram S.I., Shakova F.M. i dr. Otdalennye effekty sinteticheskogo analoga AKTG(4-10) na formirovanie prostranstvennoi pamyati u krys s ishemicheskim povrezhdeniem prefrontal'noi kory golovnogo mozga. Zhurn vyssh nervn deyat 2008; 45: 4: 458-466.
  5. Paxinos G., Watson S. Atlas of anatomy of rat brain. The rat brain in stereotaxic coordinates. San Diego: Academic Press 1986.
  6. Polezhaev L.V. Utrata i vosstanovlenie regeneratsionnoi sposobnosti organov i tkanei u zhivotnykh. M 1968.
  7. Vitvitskii V.N. Regulirovanie geneticheskikh protsessov v prirode i v eksperimente. M 2005.
  8. Brewer G. J. et al. Culter and regeneration of human neurons after brain surgery. J Neurosci Methods 2001; 1: 2: 15-23.
  9. Darsalia V. et al. Stroke induced neurogenesis in aged brain. Stroke 2005; 36: 1790-1795.
  10. Prochiant A. Neurogenesis in the adult brain: hope for brain repair? Bull Acad Natl Med 2000; 6: 1181-1189.
  11. Philippe T. Neural progenitor and stem cells in the adult central nervous system. Ann Acad Med Singapor 2006; 35: 814-820.
  12. Lishchuk V.A., Mostkova E.V. Mekhanizmy samovosstanovleniya. Valeologiya 2002; 1: 4-13.
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