Background: in the framework of the current tendency toward the further development of the socio-economic sphere in the Russian Far East (RFE), the relevant investigations aimed at creating the comfortable conditions for recreational and touristic activities as well as for rehabilitative therapy of the local population acquire the increasingly greater importance. Aim. The objective of the present study was the comprehensive evaluation of the bioclimatic comfort at the territories of interest with special reference to winter-time recreational activities and primary wellness tourism. Materials and methods. This study was designed to evaluate the health resort, recreational, and therapeutic resources of the selected areas of the Russian Far East with special reference to the data provided by the climate monitoring stations during the periods from December to March of 1965—2014. The following methods were used for the purpose: the comparative analysis of climatic information and elementary methods of mathematical statistics. Results. The evaluation of the study territory in terms of the bioclimatic comfort gave evidence that the southern regions of Primorye as well as Sakhalin island, and Kamchatka peninsula provide the most favorable conditions for the therapeutic and recreational activities, leisure and sports in the winter seasons. Conclusion. The analysis of the studied bioclimatic indices of comfort at different territories of the Russian Far East has demonstrated their great potential for the further development of recreation services, rehabilitation, sporting and touristic activities. The study has revealed the new opportunities for the enhancement of bioclimatic comfort of the region and for the improvement of the quality of life and employment of the local population.