Diagnosis of labyrinth hydrops in patients on different stages of Meniere’s disease

Kunelskaya N.L.; Manaenkova E.A.; Levina Yu.V.; Baibakova E.V.; Larionova E.V.

doi:https://doi.org/10.17116/otorino20259003124

Kunelskaya N.L.

Sverzhevky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0002-1001-2609

Manaenkova E.A.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0001-8023-4883

Levina Yu.V.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0002-1589-5623

Baibakova E.V.

Sverzevsky Research Institute of Otorhinolaryngology

SPIN RSCI: 8699-2693
Scopus AuthorID: 55806423300
ResearcherID: C-4192-2014
ORCID: 0000-0002-3430-6273

Larionova E.V.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0002-3598-4762

Diagnosis of labyrinth hydrops in patients on different stages of Meniere’s disease

Authors:

Kunelskaya N.L., Manaenkova E.A., Levina Yu.V., Baibakova E.V., Larionova E.V.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2025;90(3): 24‑29

DOI: 10.17116/otorino20259003124

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To cite this article:

Kunelskaya NL, Manaenkova EA, Levina YuV, Baibakova EV, Larionova EV. Diagnosis of labyrinth hydrops in patients on different stages of Meniere’s disease. Russian Bulletin of Otorhinolaryngology. 2025;90(3):24‑29. (In Russ.)
https://doi.org/10.17116/otorino20259003124

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

Использование инфографики авторами научных работ

OBJECTIVE

To calculate the sensitivity (Se) and specificity (Sp) indicators of clinical and instrumental diagnostic methods of labyrinth hydrops (LH) in patients with definite Meniere’s disease (MD, according to the EAONO classification, 2015).

MATERIALS

We examined 67 patients with definite MD: stage 1 — 24, stage 2 — 23, stage 3 — 20 patients, as well as 30 subjects with sensorineural hearing loss (control group) with tone hearing thresholds similar to those in patients with MD.

STUDY METHODS:

Clinical, otorhinolaryngological, otoneurological (using audiometric and vestibulometric tests) examinations, extratympanic electrocochleography, glycerol dehydration test. Statistical analysis of obtained results was performed with Statistica software package (version 10.0.1011).

RESULTS

It has been established that Se and Sp indicators of clinical and instrumental tests in patients with definite MD and confirmed LH depend on the disease stage according to neurovisualization data. Electrocochleography, audiometric curve type (ascending) and dehydration test are the most sensitive and specific for detection of LH at the first stage of MD (96%); electrocochleography, ultrasound audiometry, caloric and video impulse tests (their dissociation) — at the second stage of MD (96%); audiometric curve type (horizontal), caloric and video impulse tests and vHIT (their dissociation), registration of cervical vestibular evoked myogenic potentials (their asymmetry) — at the third stage of MD (95%).

CONCLUSIONS

The obtained results allow to optimize the diagnostic algorithm at suspicion on LH, as well as to reduce economic costs by eliminating test with low sensitivity and weak informativity.

Keywords:

Meniere’s disease

wide-band tympanometry

registration of vestibular evoked myogenic potentials (VEMPs)

labyrinth hydrops

video impulse test

Authors:

Kunelskaya N.L.

Sverzhevky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0002-1001-2609

Manaenkova E.A.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0001-8023-4883

Levina Yu.V.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0002-1589-5623

Baibakova E.V.

Sverzevsky Research Institute of Otorhinolaryngology

SPIN RSCI: 8699-2693
Scopus AuthorID: 55806423300
ResearcherID: C-4192-2014
ORCID: 0000-0002-3430-6273

Larionova E.V.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0002-3598-4762

Received:

05.06.2024

Accepted:

13.08.2024

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