Role of platelet-rich plasma in management of sensorineural hearing loss diseases

Shawky M.A.; Shawky A.A.; Zakaria N.Z.

doi:https://doi.org/10.17116/otorino2026910114

OBJECTIVE

To show the effectiveness and safety of PRP in the management of sensorineural hearing loss (SNHL) diseases.

MATERIAL AND METHODS

150 patients who had sensorineural hearing loss because of different otological diseases, such as acoustic trauma, presbycusis, idiopathic sudden SNHL, in addition to Meniere’s disease (MD). All cases received 4 times of intratympanic injections of PRP with one-week intervals between them.

RESULTS

In our research, 150 cases with SNHL diseases, as acoustic trauma, MD, presbycusis, and idiopathic sudden sensorineural hearing loss (ISSNHL) (68 (46.3%) males and 82 (54.6%) females) with age ranges from 18 to 78 years, received intratympanic injections of PRP. 50 patients with ISSNHL: 39 of them showed hearing improvement, with an average of 28 dB in pure tone audiometry (PTA) and 26% in speech discrimination. In acoustic trauma, 18 patients, 12 of them, showed hearing improvement, averaging 30 dB in PTA and 28% in speech discrimination. In presbycusis, 58 patients, 42 of them, showed an improvement in hearing of an average of 25 dB and 24% in speech discrimination. In Meniere’s disease, 24 patients, 16 of them, showed an improvement in hearing of an average of 15 dB and 5% in speech discrimination.

CONCLUSION

Platelet-rich plasma appears effective and safe for the management of sensorineural hearing loss with no systemic side effects as an oral steroid and at low cost.

Keywords:

SNHL

PRP

ISSNHL

acoustic trauma

Meniere’s disease

presbycusis

Authors:

Shawky M.A.

Al-Azhar University, Egyp

Shawky A.A.

Mansoura University, Egyp

Zakaria N.Z.

Arish University, Egyp

Received:

17.07.2024

Accepted:

14.05.2025

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