The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Pashkov A.V.

Pediatric and Child Health Research Institute of the Petrovsky National Research Center of Surgery;
Central State Medical Academy of Department of Presidential Affairs

Fatakhova M.T.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Ustinova N.V.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Namazova-Baranova L.S.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Naumova I.V.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Kunitsyna V.G.

Central State Medical Academy of Department of Presidential Affairs

Rubinshtein P.A.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Voevodina K.I.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Chirkina D.S.

Petrovsky Russian Scientific Center of Surgery

Mamedyarov A.M.

Petrovsky Russian Scientific Center of Surgery

Indicators of registration of auditory brainstem responses in children with autism spectrum disorder

Authors:

Pashkov A.V., Fatakhova M.T., Ustinova N.V., Namazova-Baranova L.S., Naumova I.V., Kunitsyna V.G., Rubinshtein P.A., Voevodina K.I., Chirkina D.S., Mamedyarov A.M.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2025;90(3): 19‑23

DOI: 10.17116/otorino20259003119

Read: 1830 times

Download PDF (RU)
Contact the author
Table of contents

INDICATORS OF REGISTRATION OF AUDITORY BRAINSTEM RESPONSES IN CHILDREN WITH AUTISM SPECTRUM DISORDER
INDICATORS OF REGISTRATION OF AUDITORY BRAINSTEM RESPONSES IN CHILDREN WITH AUTISM SPECTRUM DISORDER

To cite this article:

Pashkov AV, Fatakhova MT, Ustinova NV, et al. Indicators of registration of auditory brainstem responses in children with autism spectrum disorder. Russian Bulletin of Otorhinolaryngology. 2025;90(3):19‑23. (In Russ.)
https://doi.org/10.17116/otorino20259003119

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Elevated ABR thre­sholds in the presence of otoacoustic emissions: case series. Russian Bulletin of Otorhinolaryngology. 2026;(1):76-85
Evaluation of the effe­ctiveness of adaptation of children with autism spectrum diso­rders to dental care. Stomatology. 2025;(5):43-47
Transcranial electrostimulation as part of combination therapy for mental diso­rders. S.S. Korsakov Journal of Neurology and Psychiatry. 2026;(1):37-44
Abstract:

OBJECTIVE

To evaluate the latency of the components of the auditory brainstem responses (ABR) in children with autism spectrum disorder (ASD) in age 2-3 years in comparison with the norm.

MATERIAL AND METHODS

The research includes the results of studies of 12 children with a confirmed diagnosis of ASD, including 9 boys and 3 girls aged 24 to 33 months. To assess the auditory function all children were recorded using auditory brainstem responses with a broadband click as a stimulus. At the first stage of the study, we determined the threshold of ABR recording to exclude the presence of hearing loss. Children with hearing disorders (4 people) were not included in the study — they were allocated to a separate group for further observation. The second stage of the study was a comparative analysis of the latency of wave V in patients with ASD without hearing impairment and children with normotypic development.

RESULTS

The average latency value of the wave V in the group of children with autism spectrum disorders was 6.34 ms (Mann-Whitney U-test, p≥0.05 with a growth trend, indicating a lack of statistical significance), normally 6.75-6.90 ms. The standard deviation was 0.4 (6.37%).

DISCUSSION

The deviation of latency indicators from the norm on the screening values of the ABR stimulus can be considered a biomarker of autism spectrum disorders. To exclude or confirm ASD children with such changes should be referred for consultation to specialized specialists.

Keywords:

auditory brainstem responses
autism spectrum disorder

Authors:

Pashkov A.V.

Pediatric and Child Health Research Institute of the Petrovsky National Research Center of Surgery;
Central State Medical Academy of Department of Presidential Affairs

Fatakhova M.T.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Ustinova N.V.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Namazova-Baranova L.S.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Naumova I.V.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Kunitsyna V.G.

Central State Medical Academy of Department of Presidential Affairs

Rubinshtein P.A.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Voevodina K.I.

Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Chirkina D.S.

Petrovsky Russian Scientific Center of Surgery

Mamedyarov A.M.

Petrovsky Russian Scientific Center of Surgery

Received:

12.09.2024

Accepted:

10.02.2025

Close metadata

References:

  1. Klinicheskie rekomendatsii. Rasstrojstva autisticheskogo spektra. (In Russ.). Accessed April 29, 2025. https://cr.minzdrav.gov.ru/schema/594_3
  2. Kelsey E, Whitelaw GM, Rabidoux PC. What Audiologists Need to Know about Autism Spectrum Disorders. Seminars in Hearing. 2005;26(4):202-209.  https://doi.org/10.1055/s-2005-922442
  3. Fombonne E. The epidemiology of autism: a review. Psychological Medicine. 1999;29(4):769-786.  https://doi.org/10.1017/s0033291799008508
  4. Zeidan J, Fombonne E, Scorah J, Ibrahim A, Durkin MS, Saxena S, Yusuf A, Shih A, Elsabbagh M. Global prevalence of autism: A systematic review update. Autism Research 2022;15(5):778-790.  https://doi.org/10.1002/aur.2696
  5. Maenner MJ, Shaw KA, Bakian AV, Bilder DA, Durkin MS, Esler A, Furnier SM, Hallas L, Hall-Lande J, Hudson A, Hughes MM, Patrick M, Pierce K, Poynter JN, Salinas A, Shenouda J, Vehorn A, Warren Z, Constantino JN, DiRienzo M, Fitzgerald RT, Grzybowski A, Spivey MH, Pettygrove S, Zahorodny W, Ali A, Andrews JG, Baroud T, Gutierrez J, Hewitt A, Lee LC, Lopez M, Mancilla KC, McArthur D, Schwenk YD, Washington A, Williams S, Cogswell ME. Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2018. Morbidity and Mortality Weekly Report — Surveillance Summaries. 2021;70(11):1-16.  https://doi.org/10.15585/mmwr.ss7011a1
  6. Dawson G, Rogers S, Munson J, Smith M, Winter J, Greenson J, Donaldson A, Varley J. Randomized, controlled trial of an intervention for toddlers with autism: the Early Start Denver Model. Pediatrics. 2010;125(1):e17-23.  https://doi.org/10.1542/peds.2009-0958
  7. Ustinova NV, Namazova-Baranova LS, Baranov AA, Vishneva EA, Kaitukova EV, Turti TV, Albitskiy VY, Selimzianova LR, Gorbunova EA, Efendieva KE. Paradigm Shift: New Approaches to Understanding Autism Spectrum Disorders. Vestnik Rossijskoj akademii meditsinskikh nauk. 2023;78(6):589-600. (In Russ.). https://doi.org/10.15690/vramn12996
  8. Tavartkiladze GA, Gvelesiani TG, Cygankova ER, Daikhes NA, Yablonskiy SV, Pashkov AV. Rannee vyyavlenie i korrektsiya narushenij slukha u detej pervykh let zhizni. Metodicheskaya razrabotka. GOU VPO «Rossijskaya meditsinskaya akademiya poslediplomnogo obrazovaniya». M. 2010. (In Russ.).
  9. Pashkov AV, Naumova IV, Zelenkova IV. Metody issledovaniya slukha u detej. M.: Pediatr; 2020. (In Russ.).
  10. Tufatulin GSh, Pashkov AV, Koroleva IV, Naumova IV, Artyushin SA, Privalova TE, Belyaeva IA. Vyyavlenie i diagnostika narushenij slukha u detej pervogo goda zhizni. M.: Pediatr; 2023. (In Russ.).
  11. Rosenhall U, Nordin V, Sandström M, Ahlsén G, Gillberg C. Autism and hearing loss. Journal of Autism and Developmental Disorders. 1999;29(5):349-357.  https://doi.org/10.1023/a:1023022709710
  12. Roth DA, Muchnik C, Shabtai E, Hildesheimer M, Henkin Y. Evidence for atypical auditory brainstem responses in young children with suspected autism spectrum disorders. Developmental Medicine and Child Neurology. 2012;54(1):23-29.  https://doi.org/10.1111/j.1469-8749.2011.04149.x
  13. Moore JK. The human auditory brain stem as a generator of auditory evoked potentials. Hearing Research. 1987;29(1):33-43.  https://doi.org/10.1016/0378-5955(87)90203-6
  14. Moore JK. The human auditory brain stem: a comparative view. Hearing Research. 1987;29(1):1-32.  https://doi.org/10.1016/0378-5955(87)90202-4
  15. Chen J, Wei Z, Liang C, Liu B, Guo J, Kong X, Huang M, Peng Z, Wan G. Dysfunction of the Auditory Brainstem as a Neurophysiology Subtype of Autism Spectrum Disorder. Frontiers in Neuroscience. 2021;15:637079. https://doi.org/10.3389/fnins.2021.637079
  16. Miron O, Beam AL, Kohane IS. Auditory brainstem response in infants and children with autism spectrum disorder: A meta-analysis of wave V. Autism Reseach. 2018;11(2):355-363.  https://doi.org/10.1002/aur.1886
  17. Courchesne E, Campbell K, Solso S. Brain growth across the life span in autism: age-specific changes in anatomical pathology. Brain Research. 2011;1380:138-145.  https://doi.org/10.1016/j.brainres.2010.09.101
  18. Courchesne E, Karns CM, Davis HR, Ziccardi R, Carper RA, Tigue ZD, Chisum HJ, Moses P, Pierce K, Lord C, Lincoln AJ, Pizzo S, Schreibman L, Haas RH, Akshoomoff NA, Courchesne RY. Unusual brain growth patterns in early life in patients with autistic disorder: an MRI study. Neurology. 2001;57(2):245-54.  https://doi.org/10.1212/wnl.57.2.245
  19. Dabbous AO. Characteristics of auditory brainstem response latencies in children with autism spectrum disorders. Audiological Medicine. 2012;10:122-131.  https://doi.org/10.3109/1651386X.2012.708986
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.