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Karpishchenko S.A.

Pavlov First St. Petersburg State Medical University

Zubareva A.A.

Pavlov First St. Petersburg State Medical University

Bolozneva E.V.

Pavlov First St. Petersburg State Medical University

Savchenko E.M.

Pavlov First St. Petersburg State Medical University

Zueva E.A.

Pavlov First St. Petersburg State Medical University

Possibilities of differential diagnosis of chronic diseases of the nasal cavity after surgical treatment and topical antibiotic therapy

Authors:

Karpishchenko S.A., Zubareva A.A., Bolozneva E.V., Savchenko E.M., Zueva E.A.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2023;88(2): 44‑50

DOI: 10.17116/otorino20228802144

Read: 2749 times

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Table of contents

POSSIBILITIES OF DIFFERENTIAL DIAGNOSIS OF CHRONIC DISEASES OF THE NASAL CAVITY AFTER SURGICAL TREATMENT AND TOPICAL ANTIBIOTIC THERAPY
POSSIBILITIES OF DIFFERENTIAL DIAGNOSIS OF CHRONIC DISEASES OF THE NASAL CAVITY AFTER SURGICAL TREATMENT AND TOPICAL ANTIBIOTIC THERAPY

To cite this article:

Karpishchenko SA, Zubareva AA, Bolozneva EV, Savchenko EM, Zueva EA. Possibilities of differential diagnosis of chronic diseases of the nasal cavity after surgical treatment and topical antibiotic therapy. Russian Bulletin of Otorhinolaryngology. 2023;88(2):44‑50. (In Russ.)
https://doi.org/10.17116/otorino20228802144

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

The study was performed to assess the endoscopic state of the nasal mucosa after the use of local anti-inflammatory and antibacterial therapy, in particular, Polydexa nasal spray with phenylephrine containing Dexamethasone sodium metasulfobenzoate + Neomycin + Polymyxin B + Phenylephrine, and for the treatment of granulomatosis with polyangiitis.

MATERIAL AND METHODS

The study included 940 patients who underwent examination and treatment for chronic rhinosinusitis in the clinic of otorhinolaryngology of I.P. Pavlov SPbSMU surgical treatment of the paranasal sinuses underwent 907 patients. In the postoperative period, the first group (211 patients) underwent toileting of the nasal cavity. The second group (307 patients) received irrigation therapy. The third group (389 patients) received a topical treatment combined of Polydexa with phenylephrine. The dynamics of the condition was assessed on the 1st, 3rd and 7th days of treatment, the evaluation of the effectiveness of the treatment was carried out on the 3rd and 7th days. Differential diagnosis with granulomatosis with polyangiitis was carried out in 33 patients. All patients with granulomatosis with polyangiitis showed signs of chronic rhinosinusitis. Patients were prescribed local anti-inflammatory and antibacterial therapy with Polydexa with phenylephrine for 7 days with endoscopic control of the nasal cavity.

CONCLUSION

The use of the combined topical drug Polydexa with phenylephrine in patients with chronic rhinosinusitis and in patients with granulomatosis with polyangiitis has a positive effect, which reduces the clinical manifestations of chronic rhinosinusitis.

Keywords:

chronic rhinosinusitis
granulomatosis with polyangiitis
topic antibacterial management

Authors:

Karpishchenko S.A.

Pavlov First St. Petersburg State Medical University

Zubareva A.A.

Pavlov First St. Petersburg State Medical University

Bolozneva E.V.

Pavlov First St. Petersburg State Medical University

Savchenko E.M.

Pavlov First St. Petersburg State Medical University

Zueva E.A.

Pavlov First St. Petersburg State Medical University

Received:

23.01.2023

Accepted:

03.04.2023

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References:

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