Assessment of the population and subpopulation composition of lymphocytes and their relationship in patients with sensorineural hearing loss

Boklazhenko E.V.; Bodienkova G.M.

doi:https://doi.org/10.17116/otorino20218602116

Boklazhenko E.V.

East-Siberian Institute of Medical and Ecological Research

Bodienkova G.M.

East-Siberian Institute of Medical and Ecological Research

Assessment of the population and subpopulation composition of lymphocytes and their relationship in patients with sensorineural hearing loss

Authors:

Boklazhenko E.V., Bodienkova G.M.

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Journal: Russian Bulletin of Otorhinolaryngology. 2021;86(2): 16‑20

DOI: 10.17116/otorino20218602116

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To cite this article:

Boklazhenko EV, Bodienkova GM. Assessment of the population and subpopulation composition of lymphocytes and their relationship in patients with sensorineural hearing loss. Russian Bulletin of Otorhinolaryngology. 2021;86(2):16‑20. (In Russ.)
https://doi.org/10.17116/otorino20218602116

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

Использование инфографики авторами научных работ

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MATERIAL AND METHODS

Phenotyping of blood lymphocytes (CD3+, CD4+, CD8+, CD9+, CD16+, CD20+, CD21+, CD23+, CD25+, CD95+) was performed by indirect immunofluorescence.

RESULTS

Individuals with sensorineural hearing loss were found to have hyperactivation in both T- and B-cell links immunity.

CONCLUSIONS

The revealed changes indicate a violation of immunoregulation through factors of intercellular cooperation, and the established relationships between populations and subpopulations of lymphocytes indicate increased activity components of the immune system, their important role in the implementation of the immune response in persons with sensorineural hearing loss.

Keywords:

immune system

lymphocyte populations and subpopulations

the relationship of the cell composition of lymphocytes

professional sensorineural hearing loss

Authors:

Boklazhenko E.V.

East-Siberian Institute of Medical and Ecological Research

Bodienkova G.M.

East-Siberian Institute of Medical and Ecological Research

Received:

17.03.2020

Accepted:

24.05.2020

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References:

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