Argumentation for use of laser fluorescence spectrometry in identification of inflammatory diseases of pharynx

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Timurzieva A.B.

Kafedra bolezneĭ ukha, gorla i nosa GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova", Moskva

Nikiforova G.N.

Kafedra otorinolaringologii MONIKI im. M.F. Vladimirskogo

Svistushkin V.M.

LOR-klinika Moskovskogo oblastnogo nauchno-issledovatel'skogo klinicheskogo instituta im. M.F. Vladimirskogo, Moskva

Gerasimov A.N.

Sechenov First Moscow State Medical University, Moscow, Russia

Alexandrov M.T.

Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia

Argumentation for use of laser fluorescence spectrometry in identification of inflammatory diseases of pharynx

Authors:

Timurzieva A.B., Nikiforova G.N., Svistushkin V.M., Gerasimov A.N., Alexandrov M.T.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2020;85(3): 36‑42

DOI: 10.17116/otorino20208503136

Views: 1053

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To cite this article:

Timurzieva AB, Nikiforova GN, Svistushkin VM, Gerasimov AN, Alexandrov MT. Argumentation for use of laser fluorescence spectrometry in identification of inflammatory diseases of pharynx. Russian Bulletin of Otorhinolaryngology. 2020;85(3):36‑42. (In Russ.)
https://doi.org/10.17116/otorino20208503136

Подписка 2025 (Russian Bulletin of Otorhinolaryngology)

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Objective. The article demonstrates the experience of using laser fluorescence spectrometry (LFS) in the diagnosis of inflammatory diseases of pharynx, describes a method for recording spectra of pharyngeal tissues using the EnSpectr L405 hardware-software complex operating on the basis of laser radiation with a wavelength of 405 nm, and identifies characteristic features of spectral curves. Patients and methods. The authors presented the characteristics of the spectra from the surface of the pharynx tissue of healthy volunteers, patients with chronic tonsillitis and granular pharyngitis. Results. The most informative parameters of the spectral curves were calculated, analyzing which it is possible to identify the morphometric, metabolic, functional features of the tissue of the tonsils and posterior pharyngeal wall in normal and pathological conditions. Conclusion. The article illustrates the importance of developing highly sensitive and highly specific methods for the rapid diagnosis of inflammatory diseases of the pharynx. The presented technology can be used in clinical practice in future.

Keywords:

laser fluorescence spectrometry

inflammatory diseases of pharynx

chronic tonsillitis

granular pharyngitis

express-diagnosis

Authors:

Timurzieva A.B.

Kafedra bolezneĭ ukha, gorla i nosa GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova", Moskva

Nikiforova G.N.

Kafedra otorinolaringologii MONIKI im. M.F. Vladimirskogo

Svistushkin V.M.

LOR-klinika Moskovskogo oblastnogo nauchno-issledovatel'skogo klinicheskogo instituta im. M.F. Vladimirskogo, Moskva

Gerasimov A.N.

Sechenov First Moscow State Medical University, Moscow, Russia

Alexandrov M.T.

Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia

List of references:

Inflammatory diseases of the pharynx [Vospalitel`nye zabolevaniya glotky]. VT Palchun, ed. M.: GEOTAR-Media; 2012. (In Russ.)
Klinicheskiye rekomendatsii po profilyu «Otorinolaringologiya» [Ostryj tonzillofaringit]: standarty vedeniya patsiyentov dlya vrachey. Redaktsionnyj sovet: NA Daykhes, et al. Natsional’naya meditsinskaya assotsiatsiya otorinolaringologov. Moscow; 2014. (In Russ.)
Esposito S, Novelli A, Noviello S, D’Errico G. Treatment of acute bacterial tonsillopharyngitis in pediatrics: a meta-analysis. Infez Med. 2005;13(4):241-250. PMID: 17405235.
Saulo Duarte Passos. Diagnosing streptococcal pharyngotonsillitis in children and adolescents: the limitations of the clinical features. Revista Paulista de Pediatria. Rev paul pediatr. 2014; 32(4):283-284. https://doi.org/10.1590/S0103-05822014000400001
Murray RC, Chennupati SK. Chronic streptococcal and non-streptococcal pharyngitis. Infect Disord Drug Targets. 2012;12(4):281-285. PMID: 22338589.
Ebell MH, Smith MA, Barry HC, Ives K, Carey M. The rational clinical examination. Does this patient have strep throat? JAMA. 2000;284(22):2912-2918. PMID: 11147989.
Karpishchenko SA, Svistushkin VM. Acute and chronic tonsillitis [Khronicheskij tonzillit i angina]. SPb: Dialog; 2017. (In Russ.)
Ilina EN. Improvement of methods and means of microbiological diagnostics. Molecular measuring instruments in a modern microbiological laboratory. Klinicheskaya laboratornaya diagnostika. 2013;9:70-71. (In Russ.)
Soldatov IB, Nasibov MV. Diagnostic value of histochemical features of polymorphonuclear peripheral blood leukocytes in chronic tonsillitis. Zhurnal ushnykh, nosovykh i gorlovykh boleznej. 1989;4:42-46. (In Russ.)
Charlier-Bret N, Boucher B, Poyart C, Quesne G, Bingen E, Doit C, et al. Rapid antigen detection tests for diagnosis of group A streptococcal pharyngitis: comparative evaluation of sensitivity and practicability of 16 in vitro diagnostics medical devices performed in July 2002 by the French health products safety agency (Afssaps) as part of its market control mission. Pathol Biol (Paris). 2004;52(8):438-443. https://doi.org/10.1016/j.patbio.2004.07.013
Mogoantă CA, Ioniţă E, Pirici D, Mitroi M, Anghelina F, Ciolofan S, et al. Chronic tonsillitis: histological and immunohistochemical aspects. Rom J Morphol Embryol. 2008;49(3):381-386. PMID: 18758644.
Toledano-Sierra P. Arriola-Hernández M.,Orueta-Sánchez R. Usefulness of clinical data and rapid diagnostic tests to identify bacterial etiology in adult respiratory infections. Medwave. 2015;15(1):e6067. https://doi.org/10.5867/medwave.2015.01.6067
Li Y, Huang W, Pan J, Ye Q, Lin S, Feng S, et al. Rapid detection of nasopharyngeal cancer using Raman spectroscopy and multivariate statistic alanalysis. Molecular and Clinical Oncology. 2015;3(2):375-380. https://doi.org/10.3892/mco.2014.473
Simonato LE, Tomo S, Miyahara GI, Navarro RS, Villaverde AGJB. Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders — a pilot study. Photodiagnosis Photodyn Ther. 2017;17:1-4. https://doi.org/10.1016/j.pdpdt.2016.10.010
Sieroń A, Sieroń-Stołtny K, Kawczyk-Krupka A, Latos W, Kwiatek S, Straszak D, et al. The role of fluorescence diagnosis in clinical practice. Onco Targets Ther. 2013;6:977-982. https://doi.org/10.2147/OTT.S42074
Landau MJ, Gould DJ, Patel KM. Advances in fluorescent-image guided surgery. Ann Transl Med. 2016;4(20):392. https://doi.org/10.21037/atm.2016.10.70
Harris AT, Lungari A, Needham CJ, Smith SL, Lones MA, Fisher SE, et al. Potential for Raman spectroscopy to provide cancer screening using a peripheral blood sample. Head & Neck Oncology. 2009;1:34. https://doi.org/10.1186/1758-3284-1-34
Aleksandrov MT. Laser clinical biophotometry (theory, experiment, practice) [Lazernaya klinicheskaya biofotometriya (teoriya, eksperiment, praktika)]. M.: Technosphere; 2008. (In Russ.)
Kurzhupov MI, Loshakov VA, Filonenko EV, Zaytsev AM, Khanmurzaeva AG. Intraoperative fluorescence diagnosis and photodynamic therapy in patients with metastatic brain disesases. Zhurnal «Voprosy neirokhirurgii» im. N.N. Burdenko. 2012;2:31-38. (In Russ.)
Orosco RK, Tsien RY, Nguyen QT. Fluorescence Imaging in Surgery. IEEE reviews in biomedical engineering. 2013;6:178-187. https://doi.org/10.1109/RBME.2013.2240294
Petritskaya EN, Kulikov DA, Rogatkin DA, Guseva IA, Kulikova PA. Using of fluorescence spectroscopy for diagnosis of hypoxia and inflammatory processes in tissues. Opticheskij zhurnal. 2015;82:12. (In Russ.)
Rogatkin DA, Bychenkov OA, Lapaeva LG. The accuracy, reliability, and interpretation of the results of in vivo laser fluorescence diagnosis in the spectral range of the fluorescence of endogenous porphyrins. J Opt Technol. 2009;76:708-713. https://doi.org/10.1364/JOT.76.000708
Popov SN. Opportunities and prospects for the use of laser-conversion diagnostics in dentistry. Materials of the II scientific-practical conference of young scientists “Modern technologies in experimental and clinical dentistry” [Vozmozhnosti i perspektivy primeneniya lazerno-konversionnoj diagnostiki v stomatologii. Materialy II nauchno-prakticheskoj konferentsii molodykh uchenykh «Sovremennye tekhnologii v eksperimental’noj i klinicheskoj stomatologii»]. M. 2011:122-125. (In Russ.)
Zayko NN, Byts YuV. Pathological Physiology [Patologicheskaya fiziologiya]. M.: Medpress-Inform; 2008. (In Russ.)

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