The objective of the present study was to analyse the results of he treatment of Eustachian tube dysfunction by means of prolonged transtubal drainage of the tube lumen using a polyethylene catheter introduced immediately after the completion of the rhinosurgical intervention for the targeted delivery of pharmaceutical products. Eighty four patients with Eustachian tube dysfunction and impairment of hearing had a thin catheter introduced in the tube lumen for 7-14 days after various rhinosurgical interventions. We estimated the efficacy of the local treatment following rhinosurgery with the subsequent prolonged administration of pharmaceutical products through the intratubal drainage system. It is concluded that the introduction of a thin polyethylene drainage in the Eustachian tube lumen immediately after the rhinosurgical intervention combined with subsequent prolonged local pharmacotherapy make it possible to achieve the long-term recovery of the tube function in 80% of the patients.