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Yusef Yu.N.

Krasnov Research Institute of Eye Diseases;
I.M. Sechenov First Moscow State Medical University (Sechenov University)

Sheludchenko V.M.

Krasnov Research Institute of Eye Diseases

Budzinskaya M.V.

Krasnov Research Institute of Eye Diseases

Smirnova T.V.

Krasnov Research Institute of Eye Diseases

Kozlovskaya N.L.

Peoples’ Friendship University of Russia named after Patrice Lumumba

Durzhinskaya M.H.

Krasnov Research Institute of Eye Diseases

Krasnolutskaya E.I.

Krasnov Research Institute of Eye Diseases

Kuchieva A.M.

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Retinopathy associated with thrombotic microangiopathy of mixed origin (case report)

Authors:

Yusef Yu.N., Sheludchenko V.M., Budzinskaya M.V., Smirnova T.V., Kozlovskaya N.L., Durzhinskaya M.H., Krasnolutskaya E.I., Kuchieva A.M.

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Journal: Russian Annals of Ophthalmology. 2024;140(6): 90‑99

DOI: 10.17116/oftalma202414006190

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Table of contents

RETINOPATHY ASSOCIATED WITH THROMBOTIC MICROANGIOPATHY OF MIXED ORIGIN (CASE REPORT)
RETINOPATHY ASSOCIATED WITH THROMBOTIC MICROANGIOPATHY OF MIXED ORIGIN (CASE REPORT)

To cite this article:

Yusef YuN, Sheludchenko VM, Budzinskaya MV, et al. . Retinopathy associated with thrombotic microangiopathy of mixed origin (case report). Russian Annals of Ophthalmology. 2024;140(6):90‑99. (In Russ.)
https://doi.org/10.17116/oftalma202414006190

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

This article presents a clinical case of ocular thrombotic microangiopathy of mixed origin (antiphospholipid syndrome, malignant arterial hypertension, multigenic thrombophilia). Multimodal imaging of the fundus provides a detailed assessment of its structures. Pathological changes in the choroid, the “retinal pigment epithelium — Bruch’s membrane” complex, and the neurosensory retina, identified using fundus photography, short-wavelength autofluorescence, optical coherence tomography (OCT), and OCT angiography, are described as nonspecific in nature. Given the verification of renal thrombotic microangiopathy by nephrobiopsy in this clinical case, the likely pathogenic mechanism underlying the observed chorioretinopathy manifestations is chronic ocular thrombotic microangiopathy.

Keywords:

thrombotic microangiopathy
antiphospholipid syndrome
malignant arterial hypertension
multimodal fundus imaging
hypertensive choroidopathy
hypertensive retinopathy

Authors:

Yusef Yu.N.

Krasnov Research Institute of Eye Diseases;
I.M. Sechenov First Moscow State Medical University (Sechenov University)

Sheludchenko V.M.

Krasnov Research Institute of Eye Diseases

Budzinskaya M.V.

Krasnov Research Institute of Eye Diseases

Smirnova T.V.

Krasnov Research Institute of Eye Diseases

Kozlovskaya N.L.

Peoples’ Friendship University of Russia named after Patrice Lumumba

Durzhinskaya M.H.

Krasnov Research Institute of Eye Diseases

Krasnolutskaya E.I.

Krasnov Research Institute of Eye Diseases

Kuchieva A.M.

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Received:

26.08.2024

Accepted:

11.09.2024

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