The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Toropygin S.G.

Tver State Medical University

Mayorova E.V.

Tver State Medical University

Maslov A.N.

Tver State Medical University

Budzinskaya M.V.

Krasnov Research Institute of Eye Diseases

Influence of models of hydrophobic acrylic intraocular lenses on the development of posterior lens capsule opacifications (preliminary results)

Authors:

Toropygin S.G., Mayorova E.V., Maslov A.N., Budzinskaya M.V.

More about the authors

Journal: Russian Annals of Ophthalmology. 2020;136(6): 133‑141

DOI: 10.17116/oftalma2020136062133

Read: 3635 times

Download PDF (RU)
Contact the author
Table of contents

INFLUENCE OF MODELS OF HYDROPHOBIC ACRYLIC INTRAOCULAR LENSES ON THE DEVELOPMENT OF POSTERIOR LENS CAPSULE OPACIFICATIONS (PRELIMINARY RESULTS)
INFLUENCE OF MODELS OF HYDROPHOBIC ACRYLIC INTRAOCULAR LENSES ON THE DEVELOPMENT OF POSTERIOR LENS CAPSULE OPACIFICATIONS (PRELIMINARY RESULTS)

To cite this article:

Toropygin SG, Mayorova EV, Maslov AN, Budzinskaya MV. Influence of models of hydrophobic acrylic intraocular lenses on the development of posterior lens capsule opacifications (preliminary results). Russian Annals of Ophthalmology. 2020;136(6):133‑141. (In Russ.)
https://doi.org/10.17116/oftalma2020136062133

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Abstract:

The search for optimal design and material of the intraocular lens (IOL) that would prevent posterior capsule opacification (PCO) is still a relevant problem.

PURPOSE

To compare the influence of three models of hydrophobic acrylic IOLs on the development of PCO within one year after phaco surgery.

MATERIAL AND METHODS

The study included 72 patients (91 eyes) who were followed up for 12 months after implantation of one of three models of posterior chamber hydrophobic acrylic IOLs: MIOL-2 (Reper-NN, Russia, 24 eyes, 1st group), SA60AT and US60MP (Alcon, USA, 41 and 26 eyes, 2nd and 3rd groups, respectively). Posterior capsule images were taken and then processed with the EPCO 2000 (Evaluation of Posterior Capsular Opacification) software. The area of posterior capsule adjacent to the center of IOL’s optic of 4.0 mm in diameter was estimated. PCO score was calculated as the weighted sum of opacification areas multiplied by the degree (from 0 to 4).

RESULTS

Within 1 year of the follow-up, mean visual acuity was at least 1.0 (20/20). Significant PCO progression was observed as early as 3 months after surgery. Despite that, opacification density in all three groups at every follow-up visit did not exceed grade 2; maximal PCO score (0.0315, median) was seen 12 month after surgery in the 1st group. At the same time, differences in PCO score between the groups were not significant. Nd:YAG laser posterior capsulotomy was performed only in one patient from the 1st group 12 month after surgery. Difference in the percentage of clear posterior capsules was significant only 12 month after surgery between the 1st and 3rd groups (p=0.024).

CONCLUSION

All three models of hydrophobic acrylic IOLs showed comparably high vision outcomess during 12 months of the follow-up with somewhat better PCO score and percentage of clear posterior capsules in eyes with US60MP.

Keywords:

hydrophobic acrylic intraocular lens
secondary cataract
posterior capsule opacification

Authors:

Toropygin S.G.

Tver State Medical University

Mayorova E.V.

Tver State Medical University

Maslov A.N.

Tver State Medical University

Budzinskaya M.V.

Krasnov Research Institute of Eye Diseases

Received:

25.06.2020

Accepted:

28.07.2020

Close metadata

References:

  1. Toropygin SG, Glushkova EV. Secondary cataracts after in-the-bag intraocular lens implantation: pathomorphology, pathogenesis and types (Part 1). Russian ophthalmological journal. 2017;10(4):105-112. (In Russ.). https://doi.org/10.21516/2072-0076-2017-10-4-105-112
  2. Ursell PG, Dhariwal M, O’Boyle D, et al. 5 year incidence of YAG capsulotomy and PCO after cataract surgery with single-piece monofocal intraocular lenses: a real-world evidence study of 20,763 eyes. Eye. 2020;34: 960-968.  https://doi.org/10.1038/s41433-019-0630-9
  3. Kossack N, Schindler C, Weinhold I, et al. German claims data analysis to assess impact of different intraocular lenses on posterior capsule opacification and related healthcare costs. J Public Health. 2018;26(1):81-90.  https://doi.org/10.1007/s10389-017-0851-y
  4. Pandey SK, Apple DJ, Werner L, Maloof AJ, Milverton EJ. Posterior capsule opacification: a review of the aetiopathogenesis, experimental and clinical studies and factors of prevention. Indian J Ophthalmol. 2004;52(2): 99-112. 
  5. Bellucci R. An introduction to intraocular lenses: material, optics, haptics, design and abberations. In: Guell J.L. (ed.) Cataract. ESASO course series. Basel: Karger; 2013;3:38-55. 
  6. Pashtaev NP, Shlenskaya OV, Pozdeeva NA, et al. Native elastic intraocular lenses for surgery of small incisions. Vestnik Orenburgskogo gosudarstvennogo universiteta. 2004;5:20-23. (In Russ.).
  7. Kalauz M, Masnec S, Kordic R, et al. Posterior capsule opacification and Nd:YAG rates with two acrylic intraocular lenses after age-related cataract treatment: three-year results. Semin Ophthalmol. 2018;33(3):395-401.  https://doi.org/10.1080/08820538.2016.1247182
  8. Tetz MR, Nimsgern C. Posterior capsule opacification. Part 2: clinical findings. J Cataract Refract Surg. 1999;25(12):1662-1674. https://doi.org/10.1016/s0886-3350(99)00259-X
  9. Findl O, Buehl W, Menapace R, et al. Comparison of 4 methods for quantifying posterior capsule opacification. J Cataract Refract Surg. 2003;29(1): 106-111.  https://doi.org/10.1016/s0886-3350(02)01509-2
  10. Oshika T, Nagata T, Ishii Y. Adhesion of lens capsule to intraocular lenses of polymethylmethacrylate, silicone, and acrylic foldable materials: an experimental study. Br J Ophthalmol. 1998;82(5):549-553. 
  11. Linnola RJ, Werner L, Pandey SK, et al. Adhesion of fibronectin, vitronectin, laminin, and collagen type IV to intraocular lens materials in pseudophakic human autopsy eyes. Part 1: histological sections. J Cataract Refract Surg. 2000;26(12):1792-1806. https://doi.org/10.1016/s0886-3350(00)00748-3
  12. Ong M, Wang L, Karakelle M. Fibronectin adhesive properties of various intraocular lens materials. Invest Ophthalmol Vis Sci (ARVO Annual Meeting Abstract). 2013;54:819. 
  13. Nishi O, Nishi K. Preventing posterior capsule opacification by creating a discontinuous sharp bend in the capsule. J Cataract Refract Surg. 1999;25(4): 521-526.  https://doi.org/10.1016/s0886-3350(99)80049-2
  14. Ravalico G, Tognetto D, Palomba MA. Capsulorhexis size and posterior capsule opacification. J Cataract Refract Surg. 1996;22(1):98-103.  https://doi.org/10.1016/s0886-3350(96)80277-X
  15. Praveen MR, Shah GD, Vasavada AR, Dave KH. The effect of single-piece hydrophobic acrylic intraocular lenses on the development of posterior capsule opacification. Am J Ophthalmol. 2015;160(3):470-478.  https://doi.org/10.1016/j.ajo.2015.05.037
  16. Menapace R, Wirtitsch M, Findl O, et al. Effect of anterior capsule polishing on posterior capsule opacification and neodymium:YAG capsulotomy rates: Three-year randomized trial. J Cataract Refract Surg. 2005;31(11):2067-2075. https://doi.org/10.1016/j.jcrs.2005.08.051
  17. Mylonas G, Prskavec M, Baradaran-Dilmaghani R, et al. Effect of a single-piece and a three-piece acrylic sharp-edged IOL on posterior capsule opacification. Curr Eye Res. 2013;38(1):86-90.  https://doi.org/10.3109/02713683.2012.717242
  18. Duman R, Karel F, Özyol P, Ateş C. Effect of four different intraocular lenses on posterior capsule opacification. Int J Ophthalmol. 2015;8(1):118-121.  https://doi.org/10.3980/j.issn.2222-3959.2015.01.22
  19. Meacock WR, Spalton DJ. Effect of intraocular lens haptic compressibility on the posterior lens capsule after cataract surgery. J Cataract Refract Surg. 2001;27(9):1366-1371. https://doi.org/10.1016/s0886-3350(01)01024-0
  20. Lindholm J, Laine I, Tuuminen R. Five-year cumulative incidence and risk factors of Nd:YAG capsulotomy in 10 044 hydrophobic acrylic 1-piece and 3-piece intraocular lenses. Am J Ophthalmol. 2019;200:218-223.  https://doi.org/10.1016/j.ajo.2019.01.010
  21. Ursell PG, Dhariwal M, Majirska K. Three-year incidence of Nd:YAG capsulotomy and posterior capsule opacification and its relationship to monofocal acrylic IOL biomaterial: a UK Real World Evidence study. Eye. 2018; 32(10):1579-1589. https://doi.org/10.1038/s41433-018-0131-2
  22. Schartmüller D, Schriefl S, Schwarzenbacher L. Posterior capsule opacification and Nd:YAG laser rates with two hydrophobic acrylic single-piece IOLs. Eye. 2020;34(5):857-863.  https://doi.org/10.1038/s41433-019-0569-X
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.