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Rud’ko A.S.

Research Institute of Eye Disease, 11 A, B, Rossolimo St., Moscow, Russia, 119021

Efendieva M.Kh.

Research Institute of Eye Disease, 11 A, B, Rossolimo St., Moscow, Russia, 119021

Budzinskaia M.V.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Karpilova M.A.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Influence of vascular endothelial growth factor on angiogenesis and neurogenesis

Authors:

Rud’ko A.S., Efendieva M.Kh., Budzinskaia M.V., Karpilova M.A.

More about the authors

Journal: Russian Annals of Ophthalmology. 2017;133(3): 75‑81

DOI: 10.17116/oftalma2017133375-80

Views: 3826

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To cite this article:

Rud’ko AS, Efendieva MKh, Budzinskaia MV, Karpilova MA. Influence of vascular endothelial growth factor on angiogenesis and neurogenesis. Russian Annals of Ophthalmology. 2017;133(3):75‑81. (In Russ.)
https://doi.org/10.17116/oftalma2017133375-80

Подписка 2025 (Russian Annals of Ophthalmology)
 
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Vascular endothelial growth factor (VEGF) is known as a key mediator of angiogenesis, but there is also evidence of its broad significance in neurogenesis and neuroprotection. Cytokines of the VEGF family affect neovascularization and neural development in the brain, particularly during cerebral ischemia, in which there is a coordinated interaction of angiogenesis and neurogenesis that contributes to rapid functional recovery. This review examines the involvement of VEGF family members and their receptors in physiological and pathophysiological processes as well as the relationship between VEGF-A plasma levels and ischemic stroke.

Keywords:

vascular endothelial growth factor (VEGF)
angiogenesis
neurogenesis
neural stem cells
plasma
cerebral ischemia

Authors:

Rud’ko A.S.

Research Institute of Eye Disease, 11 A, B, Rossolimo St., Moscow, Russia, 119021

Efendieva M.Kh.

Research Institute of Eye Disease, 11 A, B, Rossolimo St., Moscow, Russia, 119021

Budzinskaia M.V.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Karpilova M.A.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

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