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Polenova N.V.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Strokova T.V.

FGBUN «Federal'nyj issledovatel'skij tsentr pitanija, biotehnologii i bezopasnosti pischi», Moskva, Rossija

Starodubova A.V.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, 2/14, Ustyinsky Passage, Moscow, Russia, 109240;
N.I. Pirogov Russian National Research Medical University, 1, Ostrovityanov St., Moscow, Russia, 117997

Characteristics of lipid metabolism and the cardiovascular system in glycogenosis types I and III

Authors:

Polenova N.V., Strokova T.V., Starodubova A.V.

More about the authors

Journal: Therapeutic Archive. 2017;89(8): 88‑94

DOI: 10.17116/terarkh201789888-94

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Table of contents

CHARACTERISTICS OF LIPID METABOLISM AND THE CARDIOVASCULAR SYSTEM IN GLYCOGENOSIS TYPES I AND III
CHARACTERISTICS OF LIPID METABOLISM AND THE CARDIOVASCULAR SYSTEM IN GLYCOGENOSIS TYPES I AND III

To cite this article:

Polenova NV, Strokova TV, Starodubova AV. Characteristics of lipid metabolism and the cardiovascular system in glycogenosis types I and III. Therapeutic Archive. 2017;89(8):88‑94. (In Russ.)
https://doi.org/10.17116/terarkh201789888-94

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Abstract:

Glycogen storage disease (GSD) is an inherited metabolic disorder characterized by early childhood lipid metabolic disturbances with potentially proatherogenic effects. The review outlines the characteristics of impaired lipid composition and other changes in the cardiovascular system in GSD types I and III. It analyzes the factors enabling and inhibiting the development of atherosclerosis in patients with GSD. The review describes the paradox of vascular resistance to the development of early atherosclerosis despite the proatherogenic composition of lipids in the patients of this group.

Keywords:

glycogen storage disease
dyslipidemia
subclinical atherosclerosis
rare (orphan) diseases
lipid paradox

Authors:

Polenova N.V.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Strokova T.V.

FGBUN «Federal'nyj issledovatel'skij tsentr pitanija, biotehnologii i bezopasnosti pischi», Moskva, Rossija

Starodubova A.V.

Federal Research Centre of Nutrition, Biotechnology and Food Safety, 2/14, Ustyinsky Passage, Moscow, Russia, 109240;
N.I. Pirogov Russian National Research Medical University, 1, Ostrovityanov St., Moscow, Russia, 117997

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