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Hilal N.R.

N.I. Lobachevsky Nizhny Novgorod National Research University, Nizhny Novgorod, Russia

Novikov D.V.

Department of Comprehensive Sanation of Oral Cavity, Centre of Stomatology and Maxillofacial Surgery

Novikov V.V.

Academician Pavlov Ryazan State Medical University, Ryazan, Russia

Karaulov A.V.

GBOU VPO Pervyĭ MGMU im. I.M. Sechenova

Cancer-testis genes in colon cancer

Authors:

Hilal N.R., Novikov D.V., Novikov V.V., Karaulov A.V.

More about the authors

Journal: Therapeutic Archive. 2017;89(5): 113‑117

DOI: 10.17116/terarkh2017895113-117

Read: 1435 times

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Table of contents

CANCER-TESTIS GENES IN COLON CANCER
CANCER-TESTIS GENES IN COLON CANCER

To cite this article:

Hilal NR, Novikov DV, Novikov VV, Karaulov AV. Cancer-testis genes in colon cancer. Therapeutic Archive. 2017;89(5):113‑117. (In Russ.)
https://doi.org/10.17116/terarkh2017895113-117

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Abstract:

The expression of cancer-testis (CT) genes varies with tumor type. There are tumors with high, low, and intermediate gene expressions. Tumor cells of different origin are characterized by ST gene co-expression. The expression of ST genes increases in later stages of tumor development in the presence of metastases. In colon cancer, the tumor samples showed most frequently MAGE-A and SSX mRNA. The peripheral blood samples displayed most commonly XAGE, MAGE-C, and SSX mRNA. In patients with colon cancer, the expression of TSP50, MAGE-A(1-6), and SSX1,2,4 genes was associated with a poor prognosis, that of MAGE-C1 and XAGE1 was related to a favorable prognosis.

Keywords:

mRNA
cancer-testis genes
colon cancer

Authors:

Hilal N.R.

N.I. Lobachevsky Nizhny Novgorod National Research University, Nizhny Novgorod, Russia

Novikov D.V.

Department of Comprehensive Sanation of Oral Cavity, Centre of Stomatology and Maxillofacial Surgery

Novikov V.V.

Academician Pavlov Ryazan State Medical University, Ryazan, Russia

Karaulov A.V.

GBOU VPO Pervyĭ MGMU im. I.M. Sechenova

Close metadata

References:

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