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Maslov L.N.

Research Institute of Cardiology, Tomsk, Russia

Tsibulnikov S.Yu.

Research Institute of Cardiology, Tomsk, Russia;
National Research Tomsk Polytechnic University, Tomsk, Russia

Tsepokina A.V.

Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia

Khutornaya M.V.

Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia

Kutikhin A.G.

Division of Experimental and Clinical Cardiology, Research Institute for Complex Issues of Cardiovascular Diseases, Sosnovy Boulevard 6, Kemerovo, 650002, Russian Federation

Tsibulnikova M.R.

Research Institute of Cardiology, Tomsk, Russia;
National Research Tomsk Polytechnic University, Tomsk, Russia

Basalay M.V.

Republican Research and Practical Center of Cardiology, Minsk, Belarus

Mrochek A.G.

Republican Scientific and Practical Center «Cardiology» Ministry of Health Republic of Belarus, 110 B, R. Luxembourg street, 220036, Minsk, Belarus

Neuroprotective and nephroprotective effects of remote postconditioning: Prospects for clinical use

Authors:

Maslov L.N., Tsibulnikov S.Yu., Tsepokina A.V., Khutornaya M.V., Kutikhin A.G., Tsibulnikova M.R., Basalay M.V., Mrochek A.G.

More about the authors

Journal: Therapeutic Archive. 2016;88(8): 121‑126

DOI: 10.17116/terarkh2016888121-126

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NEUROPROTECTIVE AND NEPHROPROTECTIVE EFFECTS OF REMOTE POSTCONDITIONING: PROSPECTS FOR CLINICAL USE
NEUROPROTECTIVE AND NEPHROPROTECTIVE EFFECTS OF REMOTE POSTCONDITIONING: PROSPECTS FOR CLINICAL USE

To cite this article:

Maslov LN, Tsibulnikov SYu, Tsepokina AV, et al. . Neuroprotective and nephroprotective effects of remote postconditioning: Prospects for clinical use. Therapeutic Archive. 2016;88(8):121‑126. (In Russ.)
https://doi.org/10.17116/terarkh2016888121-126

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The results of experimental and clinical studies strongly suggest that remote ischemic preconditioning (RIP) has no neuroprotective effect during cardiac surgery performed under extracorporeal circulation. Remote preconditioning (RP) has no neuroprotective effect in hemorrhagic stroke. A randomized multicenter study is needed to evaluate the efficiency RIP in patients with ischemic stroke. RP reduces the severity of ischemia/reperfusion kidney injury during transplantation. RIP has been established to prevent contrast-induced nephropathy. There is a need for a multicenter trial to evaluate the efficiency of RIP in patients with abdominal aortic aneurysm repair. Analysis of the presented data indicates that RIP fails to prevent cardiorenal syndrome in infants and children during cardiac surgery. The data available in the literature on the capacity of RIP to provide nephroprotective effect in patients after coronary artery bypass surgery are discordant and indicative of the advisability of a multicenter study.

Keywords:

remote ischemic preconditioning
brain
kidneys

Authors:

Maslov L.N.

Research Institute of Cardiology, Tomsk, Russia

Tsibulnikov S.Yu.

Research Institute of Cardiology, Tomsk, Russia;
National Research Tomsk Polytechnic University, Tomsk, Russia

Tsepokina A.V.

Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia

Khutornaya M.V.

Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia

Kutikhin A.G.

Division of Experimental and Clinical Cardiology, Research Institute for Complex Issues of Cardiovascular Diseases, Sosnovy Boulevard 6, Kemerovo, 650002, Russian Federation

Tsibulnikova M.R.

Research Institute of Cardiology, Tomsk, Russia;
National Research Tomsk Polytechnic University, Tomsk, Russia

Basalay M.V.

Republican Research and Practical Center of Cardiology, Minsk, Belarus

Mrochek A.G.

Republican Scientific and Practical Center «Cardiology» Ministry of Health Republic of Belarus, 110 B, R. Luxembourg street, 220036, Minsk, Belarus

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