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Fedulova M.V.

Russian Centre of Forensic Medical Expertise Ministry of Health of Russia

Kupriyanov D.D.

Russian Centre of Forensic Medical Expertise Ministry of Health of Russia

TGFβ1 antibodies application for IHC determination of injuries vitality. The experimental results

Authors:

Fedulova M.V., Kupriyanov D.D.

More about the authors

Journal: Forensic Medical Expertise. 2023;66(5): 43‑46

DOI: 10.17116/sudmed20236605143

Read: 1148 times

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Table of contents

TGFΒ1 ANTIBODIES APPLICATION FOR IHC DETERMINATION OF INJURIES VITALITY. THE EXPERIMENTAL RESULTS
TGFΒ1 ANTIBODIES APPLICATION FOR IHC DETERMINATION OF INJURIES VITALITY. THE EXPERIMENTAL RESULTS

To cite this article:

Fedulova MV, Kupriyanov DD. TGFβ1 antibodies application for IHC determination of injuries vitality. The experimental results. Forensic Medical Expertise. 2023;66(5):43‑46. (In Russ.)
https://doi.org/10.17116/sudmed20236605143

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

THE AIM OF THE STUDY

Is to examine the applicability of IHC staining method with TGFβ1 antibodies for injuries vitality determination. 72 skin autopsy samples with mechanical injuries from 12 persons were divided to 3 groups (n=24 in each group): vital injuries, postmortal injuries, control non-injured samples. A routine histological examination using standard H&E stain and IHC with TGFβ1 antibodies was performed. We concluded the positive TGFβ1 staining was in keratinocytes in vitally injured skin and the negative one in postmortally injured and control non-injured samples. The role of TGFβ1 in the injuries healing process and the further examinations of the TGFβ1 staining method application for determination of injuries vitality are discussed.

Keywords:

injuries vitality
TGFβ1
IHC
forensic pathology

Authors:

Fedulova M.V.

Russian Centre of Forensic Medical Expertise Ministry of Health of Russia

Kupriyanov D.D.

Russian Centre of Forensic Medical Expertise Ministry of Health of Russia

Received:

02.08.2022

Accepted:

03.09.2022

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References:

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  20. Receiver 02.08.2022 
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