The main goal of the research presented in the article was to increase the effectiveness of dental orthopedic rehabilitation of patients by developing and implementing a complex of digital planning of the initial stages of treatment, including diagnostic methods, modeling, and manufacturing of prototypes of dentures using modern computer technologies. Planning of diagnostics and treatment of a dental patient with the use of modern digital technologies was proposed to be divided into stages. A complex of digital planning of dental orthopedic treatment was formed, which is illustrated by clinical case analysis. The first stage is the planning of the rehabilitation stage, which includes the diagnosis of the patient’s dental status and preparation for orthopedic treatment. The second stage is 2D virtual planning of dental rows in the smile area-includes 2D visualization in the form of mandatory use of dental digital photography protocols and 2D creation of a virtual image of a smile using digital two-dimensional planning programs. The third stage includes 3D-virtual planning (mock-up) of teeth in an aesthetically significant area-included digitalization of clinical data of patients, namely, CBCT, scanning of the dentition separately and in the bite, face scanning. The fourth stage is the computer production of prototype dentures, according to the 3D virtual functional and aesthetic layout, which includes the production of prototypes of dentures by the additive method of 3D printing. At this stage, recommendations are given for the production of prototypes of dentures by 3D printing directly-in a direct way and using a silicone key-not in a direct way, obtained from a printed model of the prototype of the patient’s dentition.