Blood groups of the AB0 system, Rh factor and recurrent miscarriage

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PURPOSE OF THE STUDY

To determine the frequency of phenotypes of blood groups, Rh-factor in the population and in families with recurrent miscarriage.

MATERIAL AND METHODS

The phenotypes of blood groups according to the AB0 system and the Rh factor were studied in 347 women and 228 men — members of 347 families who applied to the Kaluga Regional Clinical Hospital for recurrent miscarriage and formed the main group. 4128 blood transfusion station donors were randomly included in the comparison group, there were 1892 women and 2236 men. To eliminate the ethnic heterogeneity of the surveyed groups, a study was made of the national composition of patients in the main group in comparison with this indicator of the population of the Kaluga region according to the All-Russian population census in 2002.

RESULTS

An increase in the number of women with blood type A (II) and Rh-negative blood in the main group was determined. However, it has been established that an increase in these indicators is not associated with Rh- and AB0-isosensitization and, most likely, is a marker of other causes of recurrent miscarriage.

CONCLUSIONS

The study of the role of blood groups of the AB0 system and the Rh factor in the occurrence of miscarriage requires additional research.

Keywords:

blood groups of the AB0 system

Rh-factor

spontaneous abortion

Authors:

Ginzburg B.G.

K.E. Tsiolkovsky Kaluga State University

Received:

14.07.2021

Accepted:

18.08.2021

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