Objective — to establish the impact of ozone-bacteriophage therapy on blood flow in the uterine arterial bed of patients with chronic endometritis. Subject and methods. A total of 100 patients aged 24 to 42 years with a diagnosis of chronic endometritis were examined. Group 1 patients (n=50) received 5—7 intrauterine irrigations with ozonized isotonic saline solution, followed by the administration of a complex pyobacteriophage into the uterine cavity. Group 2 patients (n=50) had traditional treatment with broad-spectrum antibiotics, vitamin complexes, and trace elements, as well as physiotherapy. All the patients underwent pelvic ultrasound and Doppler study of uterine vessel hemodynamics on 19 to 24 days of the cycle («the window of implantation») before and 1 month after treatment. Results. Baseline ultrasound scanning during «the window of implantation» revealed that the majority of patients had marked endometrial hypoplasia, hypovascularity of one of the uterine walls, and blood flow disorders in the arcuate, radial, and basal arteries; spiral arteries were visualized in less than one-third of the patients. After ozone-bacteriophage therapy, 80% of the patients were found to have higher uterine terminal artery visualization rates and symmetric myometrial flow restoration, lower PI, IR and S/D in the blood vessels of all calibers, ranging from the uterine to spiral arteries, and a 48.2% increase in the endometrial thickness. In Group 2, insufficiency in blood supply and signs of endometrial hypoplasia persisted in 78% of the women. Conclusion. The application of medical ozone for ozone-bacteriophage therapy has a positive effect on uterine arterial bed hemodynamics, which is of great importance for the successful treatment of patients with chronic endometritis.