Objective — to elucidate the specific features of the autonomic nervous system, by using computer dermography and predominantly locating a pathological focus on an auriculogram in patients with genital endometriosis. Subject and methods. A total of 162 patients with uterine endometriosis (a study group) and 53 apparently healthy women (a control group) were examined. Conventional studies were used to verify its diagnosis. A computer dermographic method was employed to study the specific features of the autonomic nervous system; a computer-aided auricular mapping technique was applied to locate a pathological focus on the auricular maps. Results. In the study group, segmental parasympathicotonia was found to be prevalent in endometriosis of the cervix uteri and excitability of the sympathetic portion of the autonomic nervous system was more common in internal uterine endometriosis. The method makes it possible to disclose reveal areas with maximal bioelectrical abnormalities (with the high or low values of the indicators), to locate a leading pathological focus in the body in a given time period, and to further select an exposure area (auricular acupuncture points). Conclusion. A set of studies in patients with genital endometriosis should include examination of the autonomic nervous system. The coadministration of progestins and tranquilizers as part of combination therapy is pathogenetically sound particularly in patients with endometriosis and a predominance of sympathicotonia (hyperamphotonia). The authors declare no conflicts of interest.