Facial injuries with damage to the soft tissues, eyeball, fractures of orbital walls, nasal bones and paranasal sinuses require the gentlest approach, unity of understanding the treatment tactics and transitions of care at all stages. The best result is observed when the stage of reconstruction of the facial skeleton frame is combined with the stage of restoration and drainage of the paranasal sinuses, since they are anatomically the same. The article describes the surgical treatment of a patient after mine-blast injury to the midface using the method of express prototyping of lost elements. The method involves computer-aided design of bone defects by processing skull’s computed tomograms, 3D model creation, formation of titanium implant on the model with its subsequent implantation. The advantages of a multidisciplinary approach using express prototyping of personalized titanium implants replacing defects of frontal-naso-ethmoid complex are shown.