Modern approach to the use of ultrasound elastography in secondary female infertility

Diomidova V.N.; Zakharova O.V.; Zhuravleva N.V.; Samoilova A.A.; Vinogradova V.S.

doi:https://doi.org/10.17116/repro202228061139

Diomidova V.N.

Ulyanov Chuvash State University

SPIN RSCI: 7628-8435
Scopus AuthorID: 56195523600
ResearcherID: E-4076-2018
ORCID: 0000-0002-3627-7971

Zakharova O.V.

Tambov State University named after G.R. Derzhavin;
National University of Science and Technology (MISIS);
Plekhanov Russian University of Economics

ORCID: 0000-0001-8590-2529

Zhuravleva N.V.

Ulyanov Chuvash State University

SPIN RSCI: 9314-2480
Scopus AuthorID: 57212469645
ORCID: 0000-0001-6470-7724

Samoilova A.A.

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

ORCID: 0000-0002-2059-6425

Vinogradova V.S.

Ulyanov Chuvash State University

Modern approach to the use of ultrasound elastography in secondary female infertility

Authors:

Diomidova V.N., Zakharova O.V., Zhuravleva N.V., Samoilova A.A., Vinogradova V.S.

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Journal: Russian Journal of Human Reproduction. 2022;28(6): 139‑146

DOI: 10.17116/repro202228061139

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To cite this article:

Diomidova VN, Zakharova OV, Zhuravleva NV, Samoilova AA, Vinogradova VS. Modern approach to the use of ultrasound elastography in secondary female infertility. Russian Journal of Human Reproduction. 2022;28(6):139‑146. (In Russ.)
https://doi.org/10.17116/repro202228061139

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)

Использование инфографики авторами научных работ

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PURPOSE OF THE STUDY

To substantiate the use of shear wave ultrasound elastography in assessing the state of uterine structures in women of reproductive age with secondary infertility.

MATERIALS AND METHODS

The main group (n=169) consisted of reproductive age patients with secondary infertility, who were divided into two subgroups: 68 women with genital tuberculosis involving the endometrium and 101 women with chronic endometritis without concomitant tuberculosis. The control group (n=45) were healthy women. The average age in the main group was 34.4±2.6 years, in the control group — 32.9±3.1 years. The duration of secondary infertility in N1 was 5.7±1.7 years. All the patients underwent ultrasound examination according to the shear wave elastography (2DSWE) protocol — two-dimensional shear wave elastography with elastometry (Aixplorer scanner, SuperSonic Imagine, France) per vaginam.

RESULTS

According to 2DSWE data It was found that in healthy women of reproductive age the stiffness of the endometrium (Emean 16.5 kPa; SD 1.0) had lower values than that of the endocervix (Emean 23.2 kPa; SD 1.9), (p<0.05). Myometrium stiffness in the cervical region was higher than that in its body (Emean 28.3 kPa; SD 3.0 and Emean 22.3 kPa; SD 1.7, respectively; p<0.05). At this, no potential dependence on different phases of the menstrual cycle was revealed. In patients suffering from secondary infertility with diffuse endometrial pathology, the values of endometrial stiffness were of the greatest diagnostic value and statistical significance. In large values of Young modulus of elasticity for endometrial stiffness exceeding normal values and inconsistent with the phase of a woman’s monthly cycle, and persisting for a long time without significant changes, there was a greater risk of non-conception.

CONCLUSION

The technology of two-dimensional shear wave elastography with elastometry can become an alternative opportunity for timely diagnosis of diffuse endometrial pathology in patients of reproductive age suffering from secondary infertility.

Keywords:

elastography

elastometry

shear wave

uterus

endometrium

secondary infertility

Authors:

Diomidova V.N.

Ulyanov Chuvash State University

SPIN RSCI: 7628-8435
Scopus AuthorID: 56195523600
ResearcherID: E-4076-2018
ORCID: 0000-0002-3627-7971

Zakharova O.V.

Tambov State University named after G.R. Derzhavin;
National University of Science and Technology (MISIS);
Plekhanov Russian University of Economics

ORCID: 0000-0001-8590-2529

Zhuravleva N.V.

Ulyanov Chuvash State University

SPIN RSCI: 9314-2480
Scopus AuthorID: 57212469645
ORCID: 0000-0001-6470-7724

Samoilova A.A.

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

ORCID: 0000-0002-2059-6425

Vinogradova V.S.

Ulyanov Chuvash State University

Received:

31.05.2022

Accepted:

04.10.2022

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