Comparative analysis of intellectual and mnestic disorders in patients with extracerebral tumors after surgical treatment

Kurnukhina M.Yu.

I.P. Pavlov First Saint Petersburg State Medical University

Mukhitova Yu.V.

I.P. Pavlov First Saint Petersburg State Medical University

Cherebillo V.Yu.

I.P. Pavlov First Saint Petersburg State Medical University

Isayeva E.R.

I.P. Pavlov First Saint Petersburg State Medical University

Gusev A.A.

Tambov State University named after G.R. Derzhavin;
National University of Science and Technology (MISIS)

ORCID: 0000-0002-8699-9112

Comparative analysis of intellectual and mnestic disorders in patients with extracerebral tumors after surgical treatment

Authors:

Kurnukhina M.Yu., Mukhitova Yu.V., Cherebillo V.Yu., Isayeva E.R., Gusev A.A.

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Journal: P.A. Herzen Journal of Oncology. 2021;10(1): 18‑23

DOI: 10.17116/onkolog20211001118

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To cite this article:

Kurnukhina MYu, Mukhitova YuV, Cherebillo VYu, Isayeva ER, Gusev AA. Comparative analysis of intellectual and mnestic disorders in patients with extracerebral tumors after surgical treatment. P.A. Herzen Journal of Oncology. 2021;10(1):18‑23. (In Russ.)
https://doi.org/10.17116/onkolog20211001118

Подписка 2025-2 (P.A. Herzen Journal of Oncology)

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OBJECTIVE

To comparatively analyze changes in intelligence and memory in patients with extracerebral tumors (adenoma and meningioma) of the brain after surgical treatment.

PATIENTS AND METHODS

Clinical examination was conducted in 76 patients with brain adenoma and meningioma. The patients’ diagnosis was based on clinical and laboratory data and radiation and instrumental findings. Intellectual and mnestic disorders were analyzed in the patients in the preoperative, early and late postoperative periods. The patients’ age was 22 to 65 years; the median age was 49 years. The investigators used intelligence tests, such as the Amthauer test (for individuals under 60 years of age) and Raven’s test, as well as memory tests, such as the 10 word memory test and the Wechsler memory scale.

RESULTS

Postoperative reversal of mnestic disorders was found in patients with pituitary adenoma (from 95.6% to 30.1%) and meningioma (from 96.8% to 64.5%). Despite that there was a more traumatic surgical access to remove meningiomas, no statistically significant difference in postoperative surgical changes was found between the two extracerebral tumor groups. Evaluating the intellectual changes revealed that at 3-6 months after surgical treatment, in the late postoperative period, average intelligence was less frequently recorded in patients with pituitary adenoma than in those with meningioma (p<0.05).

CONCLUSION

Comparing the two extracerebral tumor groups has revealed that surgery results in reversal of intellectual and mnestic disorders.

Keywords:

brain adenoma

meningioma

intellectual impairment

mnestic disorders

Authors:

Kurnukhina M.Yu.

I.P. Pavlov First Saint Petersburg State Medical University

Mukhitova Yu.V.

I.P. Pavlov First Saint Petersburg State Medical University

Cherebillo V.Yu.

I.P. Pavlov First Saint Petersburg State Medical University

Isayeva E.R.

I.P. Pavlov First Saint Petersburg State Medical University

Gusev A.A.

Tambov State University named after G.R. Derzhavin;
National University of Science and Technology (MISIS)

ORCID: 0000-0002-8699-9112

Received:

29.06.2020

Accepted:

21.10.2020

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