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Okhlopkov V.A.

GBOU "Omskaia gosudarstvennaia meditsinskaia akademiia" Ministerstva zdravookhraneniia Rossiĭskoĭ Federatsii

Zubareva E.Iu.

GBOU VPO "Omskaia gosudarstvennaia meditsinskaia akademiia", Omsk, 644043, Rossiĭskaia Federatsiia

Novikov Iu.A.

GBU zdravookhraneniia Omskoĭ oblasti "Klinicheskiĭ kozhno-venerologicheskiĭ dispanser", Omsk, 644001, Rossiĭskaia Federatsiia

Sukach M.S.

GBOU VPO "Omskaia gosudarstvennaia meditsinskaia akademiia", Omsk, 644043, Rossiĭskaia Federatsiia

Ivasiuk G.N.

GBU zdravookhraneniia Omskoĭ oblasti "Klinicheskiĭ kozhno-venerologicheskiĭ dispanser", Omsk, 644001, Rossiĭskaia Federatsiia

Semenova N.N.

GBU zdravookhraneniia Omskoĭ oblasti "Klinicheskiĭ kozhno-venerologicheskiĭ dispanser", Omsk, 644001, Rossiĭskaia Federatsiia

Bykova T.N.

GBU zdravookhraneniia Omskoĭ oblasti "Klinicheskiĭ kozhno-venerologicheskiĭ dispanser", Omsk, 644001, Rossiĭskaia Federatsiia

Evaluation of the clinical efficacy of acyclic synthetic nucleosides, recombinant interferon alfa-2b and lidocaine hydrochloride in combined therapy of herpetic infection

Authors:

Okhlopkov V.A., Zubareva E.Iu., Novikov Iu.A., Sukach M.S., Ivasiuk G.N., Semenova N.N., Bykova T.N.

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Journal: Russian Journal of Clinical Dermatology and Venereology. 2014;12(3): 28‑32

Read: 1447 times

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Table of contents

EVALUATION OF THE CLINICAL EFFICACY OF ACYCLIC SYNTHETIC NUCLEOSIDES, RECOMBINANT INTERFERON ALFA-2B AND LIDOCAINE HYDROCHLORIDE IN COMBINED THERAPY OF HERPETIC INFECTION
EVALUATION OF THE CLINICAL EFFICACY OF ACYCLIC SYNTHETIC NUCLEOSIDES, RECOMBINANT INTERFERON ALFA-2B AND LIDOCAINE HYDROCHLORIDE IN COMBINED THERAPY OF HERPETIC INFECTION

To cite this article:

Okhlopkov VA, Zubareva EIu, Novikov IuA, Sukach MS, Ivasiuk GN, Semenova NN, Bykova TN. Evaluation of the clinical efficacy of acyclic synthetic nucleosides, recombinant interferon alfa-2b and lidocaine hydrochloride in combined therapy of herpetic infection. Russian Journal of Clinical Dermatology and Venereology. 2014;12(3):28‑32. (In Russ.)

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

We report the results of direct open study of the efficacy and safety of combined therapy with synthetic acyclic nucleosides, recombinant interferon alfa-2b, and lidocaine hydrochloride. Material and methods. A total of 40 patients with herpes simplex were treated with the combined medication in a form of ointment for local and external application, administered 5 times a day. Results. Clinical cure was achieved in all patients. Good tolerability and safety of the drug were observed. Conclusion. The results showed clinical efficacy and safety of topical combined therapy in patients with herpetic infection.

Keywords:

herpes simplex
acyclic nucleosides
treatment with interferon
efficacy

Authors:

Okhlopkov V.A.

GBOU "Omskaia gosudarstvennaia meditsinskaia akademiia" Ministerstva zdravookhraneniia Rossiĭskoĭ Federatsii

Zubareva E.Iu.

GBOU VPO "Omskaia gosudarstvennaia meditsinskaia akademiia", Omsk, 644043, Rossiĭskaia Federatsiia

Novikov Iu.A.

GBU zdravookhraneniia Omskoĭ oblasti "Klinicheskiĭ kozhno-venerologicheskiĭ dispanser", Omsk, 644001, Rossiĭskaia Federatsiia

Sukach M.S.

GBOU VPO "Omskaia gosudarstvennaia meditsinskaia akademiia", Omsk, 644043, Rossiĭskaia Federatsiia

Ivasiuk G.N.

GBU zdravookhraneniia Omskoĭ oblasti "Klinicheskiĭ kozhno-venerologicheskiĭ dispanser", Omsk, 644001, Rossiĭskaia Federatsiia

Semenova N.N.

GBU zdravookhraneniia Omskoĭ oblasti "Klinicheskiĭ kozhno-venerologicheskiĭ dispanser", Omsk, 644001, Rossiĭskaia Federatsiia

Bykova T.N.

GBU zdravookhraneniia Omskoĭ oblasti "Klinicheskiĭ kozhno-venerologicheskiĭ dispanser", Omsk, 644001, Rossiĭskaia Federatsiia

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References:

  1. Хрянин А.А., Решетникова О.В. Распространенность вируса простого герпеса 1-го и 2-го типов в Сибири: популяционное исследование. Рос жур кож вен бол 2008; 1: 9-13 (приложение).
  2. Халдин А.А. Современные представления о клинике и терминологии дерматологического синдрома герпетической болезни. Жур вестн дерматол венерол 2008; 3-4 (приложение).
  3. Халдин А.А., Молочков А.В. Герпес-вирусные поражения кожи и слизистых (простой и опоясывающий герпес). Учебно-методическое пособие для врачей. М 2013.
  4. Egan K.P., Wu S., Wigdahl B., Jennings S.R. Immunological control of herpes simplex virus infections. J Neurovirol 2013; 19: 4: 328-345.
  5. Stoopler E.T., Balasubramaniam R. Topical and systemic therapies for oral and perioral herpes simplex virus infections. Duodecim 2013; 129: 1: 31-40.
  6. Capretti M.G., Marsico C., Lazzarotto T., Gabrielli L., Bagni A., De Angelis M., Rossini R., Faldella G. Herpes Simplex Virus 1 infection: misleading findings in an infant with disseminated disease. New Microbiol 2013; 36: 3: 307-313.
  7. Tan D.H., Murphy K., Shah P., Walmsley S.L. Herpes simplex virus type 2 and HIV disease progression: a systematic review of observational studies. BMC Infect Dis 2013; 13: 1: 502.
  8. Välimaa H., Seppänen M., Hukkanen V. Herpes simplex. Duodecim 2013; 129: 1: 31-40.
  9. Львов А.Н., Халдин А.А., Иванов О.Л. Психосоматические и психореабилитационные аспекты рецидивирующего простого герпеса. Рос жур кож вен бол 2008; 1: 25-27 (приложение).
  10. Самгин М.А., Халдин А.А. Простой герпес (дерматологические аспекты). М 2002.
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