Tracheobronchial stenting in patients with non-resectable tumors complicated by airway stenosis

Samsonyan E.Kh.; Emelyanov S.I.; Kurganov I.A.; Bogdanov D.Yu.; Sekundova M.A.; Frolova E.V.; Bashirov R.A.

doi:https://doi.org/10.17116/hirurgia202212141

Samsonyan E.Kh.

Evdokimov Moscow State University of Medicine and Dentistry;
Centrosoyuz Hospital of the Russian Federation

Emelyanov S.I.

Evdokimov Moscow State University of Medicine and Dentistry

RSCI AuthorID: 526110
Scopus AuthorID: 6603872681
ORCID: 0000-0002-2575-1842

Kurganov I.A.

Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

ORCID: 0000-0003-0968-3955

Bogdanov D.Yu.

Evdokimov Moscow State University of Medicine and Dentistry

Sekundova M.A.

Centrosoyuz Hospital of the Russian Federation

Frolova E.V.

Mechnikov North-Western State Medical University

SPIN RSCI: 1212-0030
Scopus AuthorID: 37037140300
ResearcherID: O-4134-2014
ORCID: 0000-0002-5569-5175

Bashirov R.A.

Centrosoyuz Hospital of the Russian Federation

Tracheobronchial stenting in patients with non-resectable tumors complicated by airway stenosis

Authors:

Samsonyan E.Kh., Emelyanov S.I., Kurganov I.A., Bogdanov D.Yu., Sekundova M.A., Frolova E.V., Bashirov R.A.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2022;(12): 41‑49

DOI: 10.17116/hirurgia202212141

Read: 1971 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Samsonyan EKh, Emelyanov SI, Kurganov IA, Bogdanov DYu, Sekundova MA, Frolova EV, Bashirov RA. Tracheobronchial stenting in patients with non-resectable tumors complicated by airway stenosis. Pirogov Russian Journal of Surgery. 2022;(12):41‑49. (In Russ.)
https://doi.org/10.17116/hirurgia202212141

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

Использование инфографики авторами научных работ

Close metadata

OBJECTIVE

To study the results and efficiency of tracheobronchial stenting in patients with unresectable tumors complicated by stenosis of central airways.

MATERIAL AND METHODS

We analyzed the results of tracheobronchial stenting in 23 patients with unresectable tumors complicated by stenosis of central airways between 2016 and 2021.

RESULTS

Technical and clinical success rate was 100%. No intraoperative complications were noted. Dyspnea regressed in all patients in early postoperative period. Moreover, there was objective improvement in lung ventilation with increase in lung capacity (from 2.1±0.4 to 2.7±0.5 l; p<0.05), forced expiratory volume (from 1.2±0.5 to 1.8±0.4 l; p<0.05), partial pressure of oxygen in arterial blood (from 47±7.4 to 85±6.3 mm Hg; p<0.05) and arterial oxygen saturation (from 86.1±8.2 to 93.1±5.1%; p<0.05). One patient developed massive bleeding due to tumor decay on the 3^rd day after surgery. In 2 patients, stent obturation with a «mucus plug» was observed after 2—3 postoperative days. In 3 months after surgery, 21.8% of patients had disturbances of external respiration accompanied by mild dyspnea due to granulation tissue growth. Stent migration in 3 months after endoscopic stenting was recorded in 1 patient. Three-month mortality was 26.1%.

CONCLUSION

Tracheobronchial stenting is a safe and effective minimally invasive surgical intervention. As a part of palliative care, this procedure improves functional and clinical parameters of pulmonary ventilation and reduces the incidence of complications. Thus, quality of life in patients with unresectable tumors complicated by airway stenosis is improved.

Keywords:

endoscopic tracheal stenting

endoscopic bronchial stenting

lung cancer

metal stent

palliative medicine

Authors:

Samsonyan E.Kh.

Evdokimov Moscow State University of Medicine and Dentistry;
Centrosoyuz Hospital of the Russian Federation

Emelyanov S.I.

Evdokimov Moscow State University of Medicine and Dentistry

RSCI AuthorID: 526110
Scopus AuthorID: 6603872681
ORCID: 0000-0002-2575-1842

Kurganov I.A.

Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation

ORCID: 0000-0003-0968-3955

Bogdanov D.Yu.

Evdokimov Moscow State University of Medicine and Dentistry

Sekundova M.A.

Centrosoyuz Hospital of the Russian Federation

Frolova E.V.

Mechnikov North-Western State Medical University

SPIN RSCI: 1212-0030
Scopus AuthorID: 37037140300
ResearcherID: O-4134-2014
ORCID: 0000-0002-5569-5175

Bashirov R.A.

Centrosoyuz Hospital of the Russian Federation

Received:

11.03.2022

Accepted:

10.04.2022

Close metadata

References:

Wood DE, Liu YH, Vallières E, Karmy-Jones R, Mulligan MS. Airway stenting for malignant and benign tracheobronchial stenosis. The Annals of Thoracic Surgery. 2003;76:167-174. https://doi.org/10.1016/S0003-4975(03)00033-X
Freitag L. Airway stents. In: Strausz J, Bolliger CT., eds. Interventional Pulmonology. UK: European Respiratory Society Publications. 2010;48:190-217. https://doi.org/10.1183/1025448x.ERM4810
Dutau H, Breen D, Bugalho A, Dalar L, Daniels J, Dooms C, Eberhardt R, Ek L, Encheva M, Febvre M, Hackl M, Marran S, Papai-Szekely Z, Perch M, Roglic M, Rosell A, Rozman A, Shah PL, Simon M, Szlubowski A, Stratakos G, Sundset A, Uibu T, Von Garnier C, Zaric B, Zdraveska M, Zuccatosta L, Bokan D, Arshad Husain S, Bilaceroglu S, Gasche-Soccal P, Gasparini S, Herth FJF, Munavvar M. Current practice of airway stenting in the adult population in Europe a survey of the Association of Bronchology and Interventional Pulmonology (EABIP). Respiration. 2018;95:44-54. https://doi.org/10.1159/000480152
Dutau H, Dumon JF. Airway Stenting Revisited: 30 Years, the Age of Reason? Journal of Bronchology & Interventional Pulmonology. 2017;24(4):257-259. https://doi.org/10.1097/LBR.0000000000000433
Korzheva IY, Bagatelia ZA, Chechenin GA, Gorban DG, Maltseva IM, Poddubny VV, Zhestkov KG. Modern possibilities of endoscopic stenting and recanalization of the respiratory tract in stenosing tumors of the trachea and bronchi. Moskovskij khirurgicheskiji zhurnal. 2016;4(50):39-42. (In Russ.).
Grewal HS, Dangayach NS, Ahmad U, Ghosh S, Gildea T, Mehta AC. Treatment of tracheobronchial injuries: a contemporary review. Chest Journal. 2019;155(3):595-604. https://doi.org/10.1016%2Fj.chest.2018.07.018
Backer CL, Mavroudis C, Holinger LD. Repair of congenital tracheal stenosis. Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual. 2002;5:173-186. https://doi.org/10.1053/pcsu.2002.29718
Jaiswal P, Whitaker D, Lang-Lazdunski L, Coonar A. Stenting for tracheobronchial stenosis in tuberculosis. Journal of the Royal Society of Medicine. 2005;98(1):26-28. https://doi.org/10.1258%2Fjrsm.98.1.26
Ivanovskaya KA, Muravyev VU, Ivanov AI. Endoscopic stenting of the trachea. Prakticheskaja medicina. 2013;2(67):123-125. (In Russ.).
Shulutko AM, Ovchinnicov AA, Yasnogorodsky OO, Motus IYa. Endoscopic thoracic surgery. M.: Medicina; 2006. (In Russ.).
Fuehner T, Suhling H, Greer M, Wiesner O, Dierich M, Warnecke G, Haverich A, Welte T, Gottlieb J. Biodegradable stents after lung transplantation. Transplant International. 2013;26(7):58-60. https://doi.org/10.1111/tri.12095
Dutau H, Musani AI, Laroumagne S, Darwiche K, Freitag L, Astoul P. Biodegradable Airway Stents — Bench to Bedside: A Comprehensive Review. Respiration. 2015;90(6):512-521. https://doi.org/10.1159/000442054
Mathew R, Hibare K, Dalar L, Roy EW. Tracheobronchial stent sizing and deployment practices airway stenting practices around the world: a survey study. Journal of Thoracic Disease. 2020;12(10):5495-5504. https://doi.org/10.21037/jtd-20-2080
Ayub A, Al-Ayoubi AM, Bhora FY. Stents for airway strictures: selection and results. Journal of Thoracic Disease. 2017;9(2):116-121. https://doi.org/10.21037/jtd.2017.01.56
FDA public health notification: Complications from metallic tracheal stents in patients with benign airway disorders. 2005. Accessed February 15, 2022. https://www.jsre.org/info/0801_fda.pdf
Madden BP, Loke TK, Sheth AC. Do expandable metallic airway stents have a role in the management of patients with benign tracheobronchial disease? The Annals of Thoracic Surgery. 2006;82(1):274-278. https://doi.org/10.1016/j.athoracsur.2006.02.028
Catarata MJP, Saleiro S, Araujo VS. Outcomes of airway stents in the palliative care of patients with cancer. American Journal of Hospice and Palliative Medicine. 2021;38(1):19-24. https://doi.org/10.1177%2F1049909120926466
Rafanan AL, Mehta AC. Stenting of the tracheobronchial tree. Radiologic clinics of North America. 2000;38(2):395-408. https://doi.org/10.1016/s0033-8389(05)70170-6
Drobjazgin EA, Chikinev JuV, Sudovyh IE, Peshkova IV. Endoscopic interventions in tumor of trachea. Vestnik khirurgii im. I.I. Grekova. 2017;4(176):18-21. (In Russ.).
Akram MJ, Khalid U, Bakar MA, Ashraf MB, Butt FM, Khan F. Indications and clinical outcomes of fully covered self-expandable metallic tracheobronchial stents in patients with malignant airway diseases. Expert Review of Respiratory Medicine. 2020;14(11):1173-1181. https://doi.org/10.1080/17476348.2020.1796642
Usuda K, Iwai S, Yamagata A, Lijima Y, Motono N, Takahara Y, Shinomiya Sh, Oikawa T, Mizuno Sh, Uramoto H. Clinical outcomes and survival following placement of self-expandable metallic stents for central airway stenosis and fistula. Thoracic Cancer. 2020;12(1):48-56. https://doi.org/10.1111%2F1759-7714.13707