Local management of purulent wounds with wound dressings

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Purulent-inflammatory lesions of skin and soft tissues account for 30—35% of causes of admission to surgical hospitals. In outpatient system, this value reaches 35—60%. Moreover, suppuration of wounds after elective surgery occurs in 2—5% of cases. Adequately selected drugs for local wound therapy can achieve localization of purulent process and avoid spread of infection. This review summarizes data on development, experimental and clinical testing of wound dressings over the past 10 years, presents classification options and analyzes their advantages and disadvantages. The authors emphasize higher efficacy of hydrophilic coatings, and coatings based on chitosan, collagen, methylcellulose and its derivatives are preferred. It is advisable to introduce a component with antimicrobial, anesthetic and hemostatic activity stimulating tissue regeneration into the matrix of wound dressing. The priority is introduction of antiseptic substances causing fewer side effects compared to antibiotics. Further research and development of new wound dressings is a priority in surgery considering changing landscape and development of resistance of microorganisms.

Keywords:

wound process

wound treatment

purulent wound

wound dressing

Authors:

Grigoryan A.Yu.

Kursk State Medical University

Bezhin A.I.

Kursk State Medical University

ORCID: 0000-0003-3776-9449

Pankrusheva T.A.

Kursk State Medical University

Sukovatykh B.S.

Kursk State Medical University

SPIN RSCI: 8778-1530
Scopus AuthorID: 7004581366
ORCID: 0000-0003-2197-8756

Received:

20.03.2022

Accepted:

24.05.2022

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