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Lazarenko V.A.

Kursk State Medical University, Ministry of Health of Russia, Kursk, Russia

Ivanov S.V.

State Research Institute for Complex Issues of Cardiovascular Diseases Municipal Budget Healthcare Institution, Kemerovo, Russia

Ivanov I.S.

Kursk State Medical University ,Department of surgical diseases №1

Rosberg E.P.

Department of surgical diseases №1 Medical University «Kursk State Medical University» of Ministry of Health of the Russian Federation, Kursk, Russia

Tsukanov A.V.

Kursk State Medical University ,Department of surgical diseases №1

Popova L.P.

Department of surgical diseases №1 Medical University «Kursk State Medical University» of Ministry of Health of the Russian Federation, Kursk, Russia

Tarabrin D.V.

Kursk State Medical University ,Department of surgical diseases №1

Obiedkov E.G.

Kursk State Medical University ,Department of surgical diseases №1

Collagen types ratio in prediction of postoperative ventral hernias

Authors:

Lazarenko V.A., Ivanov S.V., Ivanov I.S., Rosberg E.P., Tsukanov A.V., Popova L.P., Tarabrin D.V., Obiedkov E.G.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2017;(6): 33‑36

DOI: 10.17116/hirurgia2017633-36

Read: 1807 times

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Table of contents

COLLAGEN TYPES RATIO IN PREDICTION OF POSTOPERATIVE VENTRAL HERNIAS
COLLAGEN TYPES RATIO IN PREDICTION OF POSTOPERATIVE VENTRAL HERNIAS

To cite this article:

Lazarenko VA, Ivanov SV, Ivanov IS, et al. . Collagen types ratio in prediction of postoperative ventral hernias. Pirogov Russian Journal of Surgery. 2017;(6):33‑36. (In Russ.)
https://doi.org/10.17116/hirurgia2017633-36

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Aim. To analyze collagen types ratio in skin and aponeurosis in order to predict postoperative ventral hernias. Material and methods. The trial included 141 patients for the period 2012—2015. Group I (n=65) of patients without ventral hernias was divided into subgroup AI (primary operation, n=41) and BI (re-operation, n=24). Group II consisted of 76 patients with ventral hernias. We performed histological examination of skin and aponeurosis to define the collagen structure of connective tissue. Results. There were significant differences between collagen type I/III ratio in skin (2.81±0.52 in group I vs. 1.13±0.48 in group II) and aponeurosis (2.69±0.41 vs. 1.09±0.21, respectively, p≤0.05). We revealed strong direct correlation (r=+0.92) between aponeurosis and skin specimens in one group. Collagen type I level was 73.81±2.74% in subgroup AI and 72.03±2.47% in subgroup BI. Collagen type I was predominant (p≤0.05). Conclusion. In patients with ventral hernias collagen type I/III ratio in skin is 2.54 times lower than in patients without hernias. Significant correlation of collagen types in skin and aponeurosis (r= +0.92) allows to predict the risk of postoperative ventral hernias on basis of skin fragment.

Keywords:

ventral hernia
collagen types ratio
polarization microscopy

Authors:

Lazarenko V.A.

Kursk State Medical University, Ministry of Health of Russia, Kursk, Russia

Ivanov S.V.

State Research Institute for Complex Issues of Cardiovascular Diseases Municipal Budget Healthcare Institution, Kemerovo, Russia

Ivanov I.S.

Kursk State Medical University ,Department of surgical diseases №1

Rosberg E.P.

Department of surgical diseases №1 Medical University «Kursk State Medical University» of Ministry of Health of the Russian Federation, Kursk, Russia

Tsukanov A.V.

Kursk State Medical University ,Department of surgical diseases №1

Popova L.P.

Department of surgical diseases №1 Medical University «Kursk State Medical University» of Ministry of Health of the Russian Federation, Kursk, Russia

Tarabrin D.V.

Kursk State Medical University ,Department of surgical diseases №1

Obiedkov E.G.

Kursk State Medical University ,Department of surgical diseases №1

Close metadata

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