Celiac trunk resection in patients with pancreatic cancer and severe pain syndrome

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Aim. To show the advisability, satisfactory tolerance and good analgesic effect of surgery for pancreatic ductal carcinoma with celiac trunk invasion. Material and methods. Distal subtotal pancreatectomy with resection of celiac trunk and common hepatic artery was made in 21 patients. Results. Early postoperative complications after distal subtotal pancreatectomy with celiac trunk resection occurred in 10 (47.6%) patients. There was no postoperative mortality. Resection edges including retroperitoneal space and pancreas did not contain tumor cells according to histological examination. Complete analgesic effect was obtained in 100% of patients after distal subtotal pancreatectomy with celiac trunk resection and neurodissection. 1- and 2-year survival was 59.1% and 21.5% respectively in patients with locally advanced pancreatic ductal carcinoma who underwent distal subtotal pancreatectomy with celiac trunk resection, median — 13 months, maximum lifetime — 57 months. Conclusion. Distal subtotal pancreatectomy with resection of celiac trunk and common hepatic artery is safe, provides significant analgesic effect, increases resectability and expands the indications for pancreatectomy.

Keywords:

pancreatic cancer

celiac trunk resection

results of treatment

Authors:

Patiutko Iu.I.

Blokhin National Medical Research Center of Oncology

RSCI AuthorID: 137980
Scopus AuthorID: 55666204300
ORCID: 0000-0001-9254-1346

Abgarian M.G.

Khirurgicheskoe otdelenie opukholeĭ pecheni i podzheludochnoĭ zhelezy Rossiĭskogo onkologicheskogo nauchnogo tsentra im. N.N. Blokhina RAMN, Moskva

Kudashkin N.E.

Rossiĭskiĭ onkologicheskiĭ nauchnyĭ tsentr im. N.N. Blokhina RAMN, Moskva

SPIN RSCI: 3574-8344
Scopus AuthorID: 54885375500
ORCID: 0000-0003-0504-585X

Kotel'nikov A.G.

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