OBJECTIVE

To study the incidence and structure of congenital heart defects (CHD) in children with Down syndrome, as well as to analyze early postoperative period in these patients.

MATERIAL AND METHODS

A retrospective analysis of the electronic database of patients aged 0—17 years was performed.

RESULTS

Inpatient treatment for CHD was carried out in 6634 children including 301 ones with Down syndrome. Mean male-to-female ratio was 1.11. Isolated congenital heart defect was found in 106 (35.2%) children, combined defects — in 195 (64.8%) children. Pale-type septal CHD with arteriovenous shunting was observed in 96% of cases. Down syndrome was diagnosed in 55% of children at birth and in 45% of patients after the first month of life. CHD was verified in prenatal and postnatal period in 10% and 90% of children, respectively. At admission, severity of clinical condition was determined by heart failure. Postoperative period was favorable in 91.4% of cases. In 8.6% of patients, postoperative period was complicated by pneumonia, sepsis and acute cardiovascular failure.

CONCLUSION. R

Etrospective analysis of the incidence and structure of CHD in children with Down syndrome treated at the Federal Center for Cardiovascular Surgery (Astrakhan) can be used in planning the volume of specialized care for children with CHD.