Evaluation of conservative therapy outcomes in patients with decompensated lower limb ischemia within one-year follow-up period using WIfI classification system

Chervyakov Yu.V.; Kha Kh.N.; Klimov A.E.; Gavrilenko A.V.

doi:https://doi.org/10.17116/kardio202013041347

Chervyakov Yu.V.

Yaroslavl State Medical University

Kha Kh.N.

Peoples’ Friendship University of Russia

Klimov A.E.

Peoples’ Friendship University of Russia

ORCID: 0000-0002-0001-8003

Gavrilenko A.V.

Petrovsky Russian Research Center of Surgery;
Sechenov First Moscow State Medical University

Evaluation of conservative therapy outcomes in patients with decompensated lower limb ischemia within one-year follow-up period using WIfI classification system

Authors:

Chervyakov Yu.V., Kha Kh.N., Klimov A.E., Gavrilenko A.V.

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Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2020;13(4): 347‑354

DOI: 10.17116/kardio202013041347

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To cite this article:

Chervyakov YuV, Kha KhN, Klimov AE, Gavrilenko AV. Evaluation of conservative therapy outcomes in patients with decompensated lower limb ischemia within one-year follow-up period using WIfI classification system. Russian Journal of Cardiology and Cardiovascular Surgery. 2020;13(4):347‑354. (In Russ.)
https://doi.org/10.17116/kardio202013041347

Подписка 2026 Кардиология и сердечно-сосудистая хирургия (Russian Journal of Cardiology and Cardiovascular Surgery)

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OBJECTIVE

To assess an efficacy of prostaglandin E1 (PGE1) in complex therapy of inoperable critical lower limb ischemia within one-year follow up period using WIfI classification system.

MATERIAL AND METHODS

A retrospective, multiple-center trial included 109 patients (60 men and 49 women). Mean age was 70±7,3 years. Patients were divided into 2 groups. Group 1 (n=58) — standard therapy without PGE1, group 2 (n=51) — standard therapy with PGE1. Statistical analysis included chi-square test with Fisher’s exact test, log-rank test.

RESULTS

There were no significant between-group differences in all endpoints within one-year follow up period.

CONCLUSION

PGE1 in complex conservative treatment does not influence major amputation rate, amputation-free survival and overall mortality in patients with critical lower limb ischemia for all WIfI combinations (130, 131, 230, 231) within one-year follow up period.

Keywords:

critical lower limb ischemia

WIfI classification

conservative treatment

PGE1

Authors:

Chervyakov Yu.V.

Yaroslavl State Medical University

Kha Kh.N.

Peoples’ Friendship University of Russia

Klimov A.E.

Peoples’ Friendship University of Russia

ORCID: 0000-0002-0001-8003

Gavrilenko A.V.

Petrovsky Russian Research Center of Surgery;
Sechenov First Moscow State Medical University

Received:

10.02.2020

Accepted:

11.04.2020

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References:

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