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Leonov N.P.

FGBU "Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdrava Rossii

Karas'kov A.M.

FGBU "Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdravsotsrazvitiia Rossii

Strunin O.V.

Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina Minzdravsotsrazvitiia Rossii

Gorbatykh Iu.N.

Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina Minzdravsotsrazvitiia Rossii

Solov'ev O.N.

FGBU "Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdrava Rossii

Prokhorov S.N.

Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina Minzdravsotsrazvitiia Rossii

Impact of blood loss on severity of multiple organ failure in infants with congenital heart diseases operated under hypothermic artificial circulation

Authors:

Leonov N.P., Karas'kov A.M., Strunin O.V., Gorbatykh Iu.N., Solov'ev O.N., Prokhorov S.N.

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Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2012;5(5): 71‑74

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IMPACT OF BLOOD LOSS ON SEVERITY OF MULTIPLE ORGAN FAILURE IN INFANTS WITH CONGENITAL HEART DISEASES OPERATED UNDER HYPOTHERMIC ARTIFICIAL CIRCULATION
IMPACT OF BLOOD LOSS ON SEVERITY OF MULTIPLE ORGAN FAILURE IN INFANTS WITH CONGENITAL HEART DISEASES OPERATED UNDER HYPOTHERMIC ARTIFICIAL CIRCULATION

To cite this article:

Leonov NP, Karas'kov AM, Strunin OV, Gorbatykh IuN, Solov'ev ON, Prokhorov SN. Impact of blood loss on severity of multiple organ failure in infants with congenital heart diseases operated under hypothermic artificial circulation. Russian Journal of Cardiology and Cardiovascular Surgery. 2012;5(5):71‑74. (In Russ.)

Подписка 2025-2 (Russian Journal of Cardiology and Cardiovascular Surgery)
 
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Stepwise multiple linear regression analysis of factors, affecting the severity of multiple organ failure syndrome (MOFS) was performed in 300 infants aged up to 1 year under surgical correction of congenital heart diseases (CHD). The study revealed clear correlations between the severity of clinical status according to PELOD and P-MOD scales and the degree of hemorrhagic syndrome. It is found, that application of big volumes of red blood cell mass with long period of storage from large number of donors increases the severity of MOFS. It is estimated that great blood loss and prolonged aorta occlusion prolong the time of artificial pulmonary ventilation so can be risk factors for development of cardiopulmonary failure.

Keywords:

congenital heart diseases
artificial circulation
multiple organ failure syndrome
hemorrhagic syndrome
blood loss
blood transfusion.

Authors:

Leonov N.P.

FGBU "Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdrava Rossii

Karas'kov A.M.

FGBU "Novosibirskiĭ NII patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdravsotsrazvitiia Rossii

Strunin O.V.

Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina Minzdravsotsrazvitiia Rossii

Gorbatykh Iu.N.

Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina Minzdravsotsrazvitiia Rossii

Solov'ev O.N.

FGBU "Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdrava Rossii

Prokhorov S.N.

Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina Minzdravsotsrazvitiia Rossii

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