Objective — to evaluate the dynamics of coagulation parameters and their relationship with venous thromboembolism (VT) in patients with cardiac implantable electronic devices. Material and methods. There were 100 patients (57 menand 43 female) aged 71 (range 64—76) years. All of them underwent pacemaker implantation. Physical examination, sonography of the veins of upper and lower extremities and peripheral venous blood sampling were performed before and in 1, 6, 12 months after surgeryto evaluate prothrombin index (PI), fibrinogen, D-dimer, thrombin time (TT), activated partial thromboplastin time (APTT). Conclusion. The prevalence of VT was 9%, significant differences were noted only for preoperative D-dimer level. PI, fibrinogen, TT, APTT and D-dimer increased insignificantly within the first month after implantation followed by gradual decrease during follow-up. Patients with dual-chamber pacemakers had higher values of D-dimer, PI and lower APTT that indicates their hypercoagulable state.