The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Kaibysheva V.O.

N.I. Pirogov Russian National Research Medical University Ministry of Health of the Russian Federation;
Saveliev City Clinical Hospital No. 31 Moscow Department of Health

Shchelochenkov S.V.

Immanuel Kant Baltic Federal University;
Omsk State Medical University Ministry of Health of the Russian Federation

Shchelochenkova T.D.

Tver State Medical University Ministry of Health of the Russian Federation

Egorova I.V.

Tver State Medical University Ministry of Health of the Russian Federation

Tikhonov S.V.

North-Western State Medical University named after I.I. Mechnikov Ministry of Health of the Russian Federation

Budkina T.N.

National Medical Research Center for Children’s Health

Kuvaev R.O.

N.I. Pirogov Russian National Research Medical University Ministry of Health of the Russian Federation;
State Healthcare Institution of the Yaroslavl Region “Regional Clinical Oncological Hospital”

Kulikov K.A.

Research Institute of Human Morphology named after Academician A.P. Avtsyn Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Lokhmatov M.M.

National Medical Research Center for Children’s Health;
Sechenov First Moscow State Medical University (Sechenov University)

Ilansskaya M.V.

National Medical Research Center for Children’s Health

Maslenkina K.S.

Saveliev City Clinical Hospital No. 31 Moscow Department of Health;
Petrovsky National Research Centre of Surgery Ministry of Science and Higher Education of the Russian Federation

Malikhova O.A.

Russian Medical Academy of Continuous Professional Education Ministry of Health of the Russian Federation

Nikonov E.L.

Pirogov Russian National Research Medical University

Mikhaleva L.M.

Saveliev City Clinical Hospital No. 31 Moscow Department of Health;
Petrovsky National Research Centre of Surgery Ministry of Science and Higher Education of the Russian Federation

Fedorov E.D.

N.I. Pirogov Russian National Research Medical University Ministry of Health of the Russian Federation;
Saveliev City Clinical Hospital No. 31 Moscow Department of Health

Shapovalyants S.G.

N.I. Pirogov Russian National Research Medical University Ministry of Health of the Russian Federation;
Saveliev City Clinical Hospital No. 31 Moscow Department of Health

Eosinophilic gastritis, enteritis, and colitis: understudied subtypes within the spectrum of eosinophilic gastrointestinal disorders. A literature review

Authors:

Kaibysheva V.O., Shchelochenkov S.V., Shchelochenkova T.D., Egorova I.V., Tikhonov S.V., Budkina T.N., Kuvaev R.O., Kulikov K.A., Lokhmatov M.M., Ilansskaya M.V., Maslenkina K.S., Malikhova O.A., Nikonov E.L., Mikhaleva L.M., Fedorov E.D., Shapovalyants S.G.

More about the authors

Journal: Russian Journal of Evidence-Based Gastroenterology. 2025;14(2): 50‑67

DOI: 10.17116/dokgastro20251402150

Read: 1417 times

Download PDF (RU)
Contact the author
Table of contents

EOSINOPHILIC GASTRITIS, ENTERITIS, AND COLITIS: UNDERSTUDIED SUBTYPES WITHIN THE SPECTRUM OF EOSINOPHILIC GASTROINTESTINAL DISORDERS. A LITERATURE REVIEW
EOSINOPHILIC GASTRITIS, ENTERITIS, AND COLITIS: UNDERSTUDIED SUBTYPES WITHIN THE SPECTRUM OF EOSINOPHILIC GASTROINTESTINAL DISORDERS. A LITERATURE REVIEW

To cite this article:

Kaibysheva VO, Shchelochenkov SV, Shchelochenkova TD, et al. . Eosinophilic gastritis, enteritis, and colitis: understudied subtypes within the spectrum of eosinophilic gastrointestinal disorders. A literature review. Russian Journal of Evidence-Based Gastroenterology. 2025;14(2):50‑67. (In Russ.)
https://doi.org/10.17116/dokgastro20251402150

Подписка 2026 Доказательная гастроэнтерология (Russian Journal of Evidence-Based Gastroenterology)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Eosi­nophilic gastritis, ente­ritis, and coli­tis: unde­rstudied enti­ties within the spectrum of eosi­nophilic gastrointestinal diso­rders. Clinical series. Russian Journal of Evidence-Based Gastroenterology. 2025;(3):118-126
Abstract:

OBJECTIVE

In recent years, several key consensus documents have been published on eosinophilic gastrointestinal disorders (EGIDs). This review aims to analyze the literature and discuss core concepts, including terminology and classification, etiology, pathogenesis, and treatment of eosinophilic gastritis, enteritis, and colitis.

KEY POINTS

Eosinophilic gastrointestinal disorders are a group of immune-mediated diseases of unknown etiology, characterized by eosinophilic infiltration of the walls of hollow gastrointestinal organs—from the mucosa to the serosa—resulting in significant clinical symptoms, endoscopic findings, and, in some cases, complications such as perforation, bleeding, ascites, or intestinal obstruction. The first consensus document on EGIDs (2022) proposed standardized nomenclature based on the affected site: eosinophilic esophagitis, eosinophilic gastritis, eosinophilic enteritis, and eosinophilic colitis. The clinical presentation is highly variable and non-specific, depending on the depth of inflammation (mucosal, muscular, or serosal). Validated endoscopic criteria for eosinophilic involvement of the stomach and intestines are not currently available. Diagnosis of eosinophilic gastritis, enteritis, or colitis is based on clinical presentation, endoscopic findings, and multifocal mucosal biopsy followed by histological evaluation. There are no established treatment guidelines; empiric approaches include systemic and topical glucocorticoids, biologic therapies, and elimination diets.

CONCLUSION

The diagnosis of eosinophilic gastric and intestinal diseases remains challenging due to non-specific clinical and endoscopic features and the absence of clear histopathological criteria. These conditions are rare and not widely recognized in clinical practice. Current treatment strategies include dietary therapy, corticosteroids, and targeted biologic agents.

Keywords:

eosinophilic gastritis
eosinophilic duodenitis
eosinophilic jejunitis
eosinophilic ileitis
eosinophilic colitis

Authors:

Kaibysheva V.O.

N.I. Pirogov Russian National Research Medical University Ministry of Health of the Russian Federation;
Saveliev City Clinical Hospital No. 31 Moscow Department of Health

Shchelochenkov S.V.

Immanuel Kant Baltic Federal University;
Omsk State Medical University Ministry of Health of the Russian Federation

Shchelochenkova T.D.

Tver State Medical University Ministry of Health of the Russian Federation

Egorova I.V.

Tver State Medical University Ministry of Health of the Russian Federation

Tikhonov S.V.

North-Western State Medical University named after I.I. Mechnikov Ministry of Health of the Russian Federation

Budkina T.N.

National Medical Research Center for Children’s Health

Kuvaev R.O.

N.I. Pirogov Russian National Research Medical University Ministry of Health of the Russian Federation;
State Healthcare Institution of the Yaroslavl Region “Regional Clinical Oncological Hospital”

Kulikov K.A.

Research Institute of Human Morphology named after Academician A.P. Avtsyn Russian Scientific Center of Surgery named after Academician B.V. Petrovsky

Lokhmatov M.M.

National Medical Research Center for Children’s Health;
Sechenov First Moscow State Medical University (Sechenov University)

Ilansskaya M.V.

National Medical Research Center for Children’s Health

Maslenkina K.S.

Saveliev City Clinical Hospital No. 31 Moscow Department of Health;
Petrovsky National Research Centre of Surgery Ministry of Science and Higher Education of the Russian Federation

Malikhova O.A.

Russian Medical Academy of Continuous Professional Education Ministry of Health of the Russian Federation

Nikonov E.L.

Pirogov Russian National Research Medical University

Mikhaleva L.M.

Saveliev City Clinical Hospital No. 31 Moscow Department of Health;
Petrovsky National Research Centre of Surgery Ministry of Science and Higher Education of the Russian Federation

Fedorov E.D.

N.I. Pirogov Russian National Research Medical University Ministry of Health of the Russian Federation;
Saveliev City Clinical Hospital No. 31 Moscow Department of Health

Shapovalyants S.G.

N.I. Pirogov Russian National Research Medical University Ministry of Health of the Russian Federation;
Saveliev City Clinical Hospital No. 31 Moscow Department of Health

Received:

11.03.2025

Accepted:

11.04.2025

Close metadata

References:

  1. Papadopoulou A, Amil-Dias J, Auth MK, Chehade M, Collins MH, Gupta SK, Gutiérrez-Junquera C, Orel R, Vieira MC, Zevit N, Atkins D, Bredenoord AJ, Carneiro F, Dellon ES, Gonsalves N, Menard-Katcher C, Koletzko S, Liacouras C, Marderfeld L, Oliva S, Ohtsuka Y, Rothenberg ME, Strauman A, Thapar N, Yang GY, Furuta GT. Joint ESPGHAN/NASPGHAN Guidelines on Childhood Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis. Journal of Pediatric Gastroenterology and Nutrition. 2024;78(1):122-152.  https://doi.org/10.1097/MPG.0000000000003877
  2. Barchi A, Vespa E, Passaretti S, Dell’Anna G, Fasulo E, Yacoub MR, Albarello L, Sinagra E, Massimino L, Ungaro F, Danese S, Mandarino FV. The Dual Lens of Endoscopy and Histology in the Diagnosis and Management of Eosinophilic Gastrointestinal Disorders-A Comprehensive Review. Diagnostics (Basel). 2024;14(8):858.  https://doi.org/10.3390/diagnostics14080858
  3. Dellon ES, Bortey E, Chang AT, Paterson CA, Turner K, Genta RM. Determination of Optimal Eosinophil Thresholds for Diagnosis of Eosinophilic Gastritis and Duodenitis: A Pooled Analysis of 4 Prospective Studies. Clinical and Translational Gastroenterology. 2024;15(1):e00656. https://doi.org/10.14309/ctg.0000000000000656
  4. Turner KO, Sinkre RA, Neumann WL, Genta RM. Primary Colonic Eosinophilia and Eosinophilic Colitis in Adults. American Journal of Surgical Pathology. 2017;41(2):225-233.  https://doi.org/10.1097/PAS.0000000000000760
  5. Dellon ES, Gonsalves N, Abonia JP, Alexander JA, Arva NC, Atkins D, Attwood SE, Auth MKH, Bailey DD, Biederman L, Blanchard C, Bonis PA, Bose P, Bredenoord AJ, Chang JW, Chehade M, Collins MH, Di Lorenzo C, Dias JA, Dohil R, Dupont C, Falk GW, Ferreira CT, Fox AT, Genta RM, Greuter T, Gupta SK, Hirano I, Hiremath GS, Horsley-Silva JL, Ishihara S, Ishimura N, Jensen ET, Gutiérrez-Junquera C, Katzka DA, Khoury P, Kinoshita Y, Kliewer KL, Koletzko S, Leung J, Liacouras CA, Lucendo AJ, Martin LJ, McGowan EC, Menard-Katcher C, Metz DC, Miller TL, Moawad FJ, Muir AB, Mukkada VA, Murch S, Nhu QM, Nomura I, Nurko S, Ohtsuka Y, Oliva S, Orel R, Papadopoulou A, Patel DA, Pesek RD, Peterson KA, Philpott H, Putnam PE, Richter JE, Rosen R, Ruffner MA, Safroneeva E, Schreiner P, Schoepfer A, Schroeder SR, Shah N, Souza RF, Spechler SJ, Spergel JM, Straumann A, Talley NJ, Thapar N, Vandenplas Y, Venkatesh RD, Vieira MC, von Arnim U, Walker MM, Wechsler JB, Wershil BK, Wright BL, Yamada Y, Yang GY, Zevit N, Rothenberg ME, Furuta GT, Aceves SS. International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature. Clinical Gastroenterology and Hepatology. 2022;20(11):2474-2484.e3.  https://doi.org/10.1016/j.cgh.2022.02.017
  6. Mansoor E, Saleh MA, Cooper GS. Prevalence of Eosinophilic Gastroenteritis and Colitis in a Population-Based Study, From 2012 to 2017. Clinical Gastroenterology and Hepatology. 2017;15(11): 1733-1741. https://doi.org/10.1016/j.cgh.2017.05.050
  7. Jensen ET, Martin CF, Kappelman MD, Dellon ES. Prevalence of Eosinophilic Gastritis, Gastroenteritis, and Colitis: Estimates from a National Administrative Database. Journal of Pediatric Gastroenterology and Nutrition. 2016;62(1):36-42.  https://doi.org/10.1097/MPG.0000000000000865
  8. Marasco G, Visaggi P, Vassallo M, Fiocca M, Cremon C, Barbaro MR, De Bortoli N, Bellini M, Stanghellini V, Savarino EV, Barbara G. Current and Novel Therapies for Eosinophilic Gastrointestinal Diseases. International Journal of Molecular Sciences. 2023;24(20):15165. https://doi.org/10.3390/ijms242015165
  9. Kornienko EA, Moiseenkova YuA, Volkova NL, Loboda TB. Eosinophilic disorders of the gastrointestinal tract: clinical manifestations, diag-nosis and treatment. Almanac of Clinical Medicine. 2018;46(5):482-496. (In Russ.). https://doi.org/10.18786/2072-0505-2018-46-5-482-496
  10. Caldwell JM, Collins MH, Stucke EM, Putnam PE, Franciosi JP, Kushner JP, Abonia JP, Rothenberg ME. Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome. Journal of Allergy and Clinical Immunology. 2014;134(5): 1114-1124. https://doi.org/10.1016/j.jaci.2014.07.026
  11. Foroughi S, Foster B, Kim N, Bernardino LB, Scott LM, Hamilton RG, Metcalfe DD, Mannon PJ, Prussin C. Anti-IgE treatment of eosinophil-associated gastrointestinal disorders. Journal of Allergy and Clinical Immunology. 2007;120(3):594-601.  https://doi.org/10.1016/j.jaci.2007.06.015
  12. Shoda T, Wen T, Caldwell JM, Collins MH, Besse JA, Osswald GA, Abonia JP, Arva NC, Atkins D, Capocelli KE, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Mukkada VA, Putnam PE, Sheridan RM, Rudman Spergel AK, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Molecular, endoscopic, histologic, and circulating biomarker-based diagnosis of eosinophilic gastritis: Multi-site study. Journal of Allergy and Clinical Immunology. 2020;145(1):255-269.  https://doi.org/10.1016/j.jaci.2019.11.007
  13. Klein NC, Hargrove RL, Sleisenger MH, Jeffries GH. Eosinophilic gastroenteritis. Medicine (Baltimore). 1970;49(4):299-319.  https://doi.org/10.1097/00005792-197007000-00003
  14. Talley NJ, Shorter RG, Phillips SF, Zinsmeister AR. Eosinophilic gastroenteritis: a clinicopathological study of patients with disease of the mucosa, muscle layer, and subserosal tissues. Gut. 1990;31(1):54-58.  https://doi.org/10.1136/gut.31.1.54
  15. Pineton de Chambrun G, Gonzalez F, Canva JY, Gonzalez S, Houssin L, Desreumaux P, Cortot A, Colombel JF. Natural history of eosinophilic gastroenteritis. Clinical Gastroenterology and Hepatology. 2011;9(11):950-956.e1.  https://doi.org/10.1016/j.cgh.2011.07.017
  16. Tien FM, Wu JF, Jeng YM, Hsu HY, Ni YH, Chang MH, Lin DT, Chen HL. Clinical features and treatment responses of children with eosinophilic gastroenteritis. Pediatrics and Neonatology. 2011;52(5):272-278.  https://doi.org/10.1016/j.pedneo.2011.06.006
  17. Walker MM, Potter M, Talley NJ. Eosinophilic gastroenteritis and other eosinophilic gut diseases distal to the oesophagus. Lancet. Gastroenterology and Hepatology. 2018;3(4):271-280.  https://doi.org/10.1016/S2468-1253(18)30005-0
  18. Zammit SC, Cachia M, Sapiano K, Gauci J, Montefort S, Ellul P. Eosinophilic gastrointestinal disorder: is it what it seems to be? Annals of Gastroenterology. 2018;31(4):475-479.  https://doi.org/10.20524/aog.2018.0263
  19. Macaigne G. Eosinophilic colitis in adults. Clinics and Research in Hepatology and Gastroenterology. 2020;44(5):630-637.  https://doi.org/10.1016/j.clinre.2020.02.019
  20. Pesek RD, Reed CC, Muir AB, Fulkerson PC, Menard-Katcher C, Falk GW, Kuhl J, Martin EK, Magier AZ, Ahmed F, Demarshall M, Gupta A, Gross J, Ashorobi T, Carpenter CL, Krischer JP, Gonsalves N, Spergel JM, Gupta SK, Furuta GT, Rothenberg ME, Dellon ES; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Increasing Rates of Diagnosis, Substantial Co-Occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis, and Colitis Based on 10-Year Data Across a Multicenter Consortium. American Journal of Gastroenterology. 2019;114(6):984-994.  https://doi.org/10.14309/ajg.0000000000000228
  21. Fujiwara Y, Tanoue K, Higashimori A, Nishida Y, Maruyama M, Itani S, Ominami M, Nadatani Y, Fukunaga S, Otani K, Hosomi S, Tanaka F, Kamata N, Nagami Y, Taira K, Machida H, Tanigawa T, Watanabe T, Ohsawa M; F-Study group. Endoscopic findings of gastric lesions in patients with eosinophilic gastrointestinal disorders. Endoscopy International Open. 2020;8(12):E1817-E1825. https://doi.org/10.1055/a-1268-7312
  22. Pesek RD, Reed CC, Collins MH, Muir AB, Fulkerson PC, Menard-Katcher C, Falk GW, Kuhl J, Magier AZ, Ahmed FN, Demarshall M, Gupta A, Gross J, Ashorobi T, Carpenter CL, Krischer JP, Gonsalves N, Hirano I, Spergel JM, Gupta SK, Furuta GT, Rothenberg ME, Dellon ES; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Association Between Endoscopic and Histologic Findings in a Multicenter Retrospective Cohort of Patients with Non-esophageal Eosinophilic Gastrointestinal Disorders. Digestive Diseases and Sciences. 2020;65(7):2024-2035. https://doi.org/10.1007/s10620-019-05961-4
  23. Lwin T, Melton SD, Genta RM. Eosinophilic gastritis: histopathological characterization and quantification of the normal gastric eosinophil content. Modern Pathology. 2011;24(4):556-563.  https://doi.org/10.1038/modpathol.2010.221
  24. Hirano I, Collins MH, King E, Sun Q, Chehade M, Abonia JP, Bonis PA, Capocelli KE, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Leung J, Katzka D, Menard-Katcher P, Khoury P, Klion A, Mukkada VA, Peterson K, Shoda T, Rudman-Spergel AK, Spergel JA, Yang GY, Rothenberg ME, Aceves SS, Furuta GT; CEGIR investigators. Prospective Endoscopic Activity Assessment for Eosinophilic Gastritis in a Multisite Cohort. American Journal of Gastroenterology. 2022;117(3):413-423.  https://doi.org/10.14309/ajg.0000000000001625
  25. Dellon ES, Peterson KA, Murray JA, Falk GW, Gonsalves N, Chehade M, Genta RM, Leung J, Khoury P, Klion AD, Hazan S, Vaezi M, Bledsoe AC, Durrani SR, Wang C, Shaw C, Chang AT, Singh B, Kamboj AP, Rasmussen HS, Rothenberg ME, Hirano I. Anti-Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis. New England Journal of Medicine. 2020;383(17):1624-1634. https://doi.org/10.1056/NEJMoa2012047
  26. Sasaki Y, Abe Y, Mizumoto N, Nomura E, Ueno Y. Small Bowel Endoscopic Features of Eosinophilic Gastroenteritis. Diagnostics (Basel). 2022;13(1):113.  https://doi.org/10.3390/diagnostics13010113
  27. Raffaele A, Vatta F, Votto M, Licari A, Ruffoli M, Brunero M, Marseglia G, Riccipetitoni G. Eosinophilic colitis in children: a new and elusive enemy? Pediatric Surgery International. 2021;37(4):485-490.  https://doi.org/10.1007/s00383-020-04832-8
  28. Díaz Del Arco C, Taxonera C, Muñoz LE, Olivares D, Fernández Aceñero MJ. Eosinophilic colitis: experience in a large tertiary hospital. Romanian Journal of Morphology and Embryology. 2017;58(3):783-789. 
  29. Reggiani Bonetti L, Leoncini G, Daperno M, Principi MB, Baronchelli C, Manenti S, Caprioli F, Armuzzi A, Caputo A, Parente P, Cadei M, Villanacci V. Histopathology of non-IBD colitis practical recommendations from pathologists of IG-IBD Group. Digestive and Liver Disease. 2021;53(8):950-957.  https://doi.org/10.1016/j.dld.2021.01.026
  30. Visaggi P, Ghisa M, Barberio B, Maniero D, Greco E, Savarino V, Black CJ, Ford AC, de Bortoli N, Savarino E. Treatment Trends for Eosinophilic Esophagitis and the Other Eosinophilic Gastrointestinal Diseases: Systematic Review of Clinical Trials. Digestive and Liver Disease. 2023;55(2):208-222.  https://doi.org/10.1016/j.dld.2022.05.004
  31. Dellon ES, Gonsalves N, Rothenberg ME, Hirano I, Chehade M, Peterson KA, Falk GW, Murray JA, Gehman LT, Chang AT, Singh B, Rasmussen HS, Genta RM. Determination of Biopsy Yield That Optimally Detects Eosinophilic Gastritis and/or Duodenitis in a Randomized Trial of Lirentelimab. Clinical Gastroenterology and Hepatology. 2022;20(3):535-545.e15.  https://doi.org/10.1016/j.cgh.2021.05.053
  32. Turner KO, Collins MH, Walker MM, Genta RM. Quantification of Mucosal Eosinophils for the Histopathologic Diagnosis of Eosinophilic Gastritis and Duodenitis: A Primer for Practicing Pathologists. American Journal of Surgical Pathology. 2022;46(4): 557-566.  https://doi.org/10.1097/PAS.0000000000001843
  33. Lucendo AJ, Serrano-Montalbán B, Arias Á, Redondo O, Tenias JM. Efficacy of Dietary Treatment for Inducing Disease Remission in Eosinophilic Gastroenteritis. Journal of Pediatric Gastroenterology and Nutrition. 2015;61(1):56-64.  https://doi.org/10.1097/MPG.0000000000000766
  34. Lee CM, Changchien CS, Chen PC, Lin DY, Sheen IS, Wang CS, Tai DI, Sheen-Chen SM, Chen WJ, Wu CS. Eosinophilic gastroenteritis: 10 years experience. American Journal of Gastroenterology. 1993;88(1):70-74. 
  35. Mori A, Enweluzo C, Grier D, Badireddy M. Eosinophilic gastroenteritis: review of a rare and treatable disease of the gastrointestinal tract. Case Reports in Gastroenterology. 2013;7(2):293-298.  https://doi.org/10.1159/000354147
  36. Choi JS, Choi SJ, Lee KJ, Kim A, Yoo JK, Yang HR, Moon JS, Chang JY, Ko JS, Kang GH. Clinical Manifestations and Treatment Outcomes of Eosinophilic Gastroenteritis in Children. Pediatric Gastroenterology, Hepatology and Nutrition. 2015;18(4): 253-260.  https://doi.org/10.5223/pghn.2015.18.4.253
  37. Sheikh RA, Prindiville TP, Pecha RE, Ruebner BH. Unusual presentations of eosinophilic gastroenteritis: case series and review of literature. World Journal of Gastroenterology. 2009;15(17):2156-2161. https://doi.org/10.3748/wjg.15.2156
  38. Tan AC, Kruimel JW, Naber TH. Eosinophilic gastroenteritis treated with non-enteric-coated budesonide tablets. European Journal of Gastroenterology and Hepatology. 2001;13(4):425-427.  https://doi.org/10.1097/00042737-200104000-00021
  39. Kennedy K, Muir AB, Grossman A, Brown-Whitehorn T, Cianferoni A, Spergel JM, Furuta GT, Wilkins BJ, Shuker M, Ruffner MA. Modified oral enteric-coated budesonide regimens to treat pediatric eosinophilic gastroenteritis, a single center experience. Journal of Allergy and Clinical Immunology. 2019;7(6):2059-2061. https://doi.org/10.1016/j.jaip.2019.01.053
  40. Ammoury RF, Rosenman MB, Roettcher D, Gupta SK. Incidental gastric eosinophils in patients with eosinophilic esophagitis: do they matter? Journal of Pediatric Gastroenterology and Nutrition. 2010;51(6):723-726.  https://doi.org/10.1097/MPG.0b013e3181d98e6c
  41. Ko HM, Morotti RA, Yershov O, Chehade M. Eosinophilic gastritis in children: clinicopathological correlation, disease course, and response to therapy. American Journal of Gastroenterology. 2014;109(8):1277-1285. https://doi.org/10.1038/ajg.2014.166
  42. Dellon ES, Spergel JM. Biologics in eosinophilic gastrointestinal diseases. Annals of Allergy, Asthma and Immunology. 2023; 130(1):21-27.  https://doi.org/10.1016/j.anai.2022.06.015
  43. Youngblood BA, Brock EC, Leung J, Falahati R, Bryce PJ, Bright J, Williams J, Shultz LD, Greiner DL, Brehm MA, Bebbington C, Tomasevic N. AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice. International Archives of Allergy and Immunology. 2019;180(2):91-102.  https://doi.org/10.1159/000501637
  44. Kliewer KL, Murray-Petzold C, Collins MH, Abonia JP, Bolton SM, DiTommaso LA, Martin LJ, Zhang X, Mukkada VA, Putnam PE, Kellner ES, Devonshire AL, Schwartz JT, Kunnathur VA, Rosenberg CE, Lyles JL, Shoda T, Klion AD, Rothenberg ME. Benralizumab for eosinophilic gastritis: a single-site, randomised, double-blind, placebo-controlled, phase 2 trial. Lancet. Gastroenterology and Hepatology. 2023;8(9):803-815.  https://doi.org/10.1016/S2468-1253(23)00145-0
  45. Kim HP, Reed CC, Herfarth HH, Dellon ES. Vedolizumab Treatment May Reduce Steroid Burden and Improve Histology in Patients with Eosinophilic Gastroenteritis. Clinical Gastroenterology and Hepatology. 2018;16(12):1992-1994. https://doi.org/10.1016/j.cgh.2018.03.024
  46. Foster B, Foroughi S, Yin Y, Prussin C. Effect of anti-IgE therapy on food allergen specific T cell responses in eosinophil associated gastrointestinal disorders. Clinical and Molecular Allergy. 2011;9(1):7.  https://doi.org/10.1186/1476-7961-9-7
  47. Dupilumab in Eosinophilic Gastritis. Accessed February 26, 2025. https://clinicaltrials.gov/study/NCT03678545?cond=Eosinophilic%20Esophagitis&page=2&rank=185
  48. A Trial to Learn if Dupilumab is Safe for and Helps Adult and Adolescent Participants With Eosinophilic Gastritis with or Without Eosinophilic Duodenitis (ENGAGE). Accessed February 26, 2025. https://clinicaltrials.gov/study/NCT05831176?cond=Eosinophilic%20Esophagitis&page=3&rank=202
  49. A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared with Placebo in Participants Aged ≥18 Years with Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab)). Accessed February 26, 2025. https://clinicaltrials.gov/study/NCT05731128?cond=Eosinophilic%20Gastroenteritis&intr=Dupilumab&rank=13
  50. Kajbysheva VO, Drapkina OM, Berns SA, Kashin SV, Fedorov ED, Mihaleva LM, Maslenkina KS, Nikonov EL, SHepel’ RN. Diagnostika i lechenie eozinofil‘nogo ezofagita. Metodicheskie rekomendacii. M.: ROPNIZ; 2024. (In Russ.). https://doi.org/10.15829/ROPNIZ-k7-2024
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.